TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 164

Pharmaceutical Substances Syntheses, Patents, Applications - Part 164. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Pifarnine P 1631 3-picolyl-omine n c2h5 3 Reference s FR 2 100 850 Manetti Roberts appl. I-prior. . DE 2 506 209 Manetti Roberts appl. . US 3 973 026 Manetti Roberts prior. . BE 851 967 Manetti Roberts appl. . Seller R. et al. Chim. Ther. CHTPBA 6 203 1971 . Formulation s tabl. 300 mg as hydrate Trade Name s I Plactidil Samil Pifarnine ATC A02B Use peptic ulcer therapeutic gastric acid secretion inhibitor RN 56208-01-6 MF C27H4 IN2O2 MW LD5 500 mg kg M . CN l- l 3-benzodioxol-5-ylmethyl -4- 3 7 ll-trimethyl-2 6 10-dodecatrienyl piperazine 1 -piperonyl-piperozine Reference s ES 452 269 Boehringer Mannh. appl. . Bianchetti A. et al. Eur. J. Med. Chem. EJMCA5 9 555 1974 10 585 1975 . Formulation s 50 mg Trade Name s 1 Pifazin Pierrel wfm 1632 P Pifoxime Pifoxime Pixifenidum ATC MOI AB Use anti-inflammatory RN 31224-92-7 MF C 5H20N2O3 MW LD5o 1 g kg M . CN 1 - 4- 1 - hydroxyimino ethyl phenoxy acetyl piperidine HOOCx CI HjC OH H2SO4 ---------------- 4-acetylphenoxy- chloroacetic 4 -hydroxy- ac td acetophenone acetic acid Reference s US 3 907 792 A. Mieville CH-prior. . Trade Name s F Flamanil Salvoxyl- Wander wfm Piketoprofen ATC M02AA Use topical non-steroidal antiinflammatory and analgesic ketoprofen derivative RN 60576-13-8 MF C22H20N2O2 MW CN 3-benzoyl-a-methyl-N- 4-methyl 2-pyridinyl benzeneacetamide monohydrochloride RN 59512-37-7 MF C22H20N2O2 HC1 MW methylpyridine tl Piketoprofen ketoprofen 1 q. v. Pildralazine P 1633 1- PCIj 2. I -------------- 1. phosphorous trichloride Reference s a GB 1 436 502 A. Gallardo SA appl. E-prior. . b BE 882 711 Fordonal SA appl. E-prior. . Formulation s aerosol 20 mg ml Trade Name s E Calmatel Almirall 1985 Pildralazine ATC C01D Use hypotensive vasodilator RN 64000-73-3 MF CsH NjO MW CN 6- 2-hydroxypropyl methylamino -3 2 -pyridazinone hydrazone OH 3 h3c

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