TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 209

Pharmaceutical Substances Syntheses, Patents, Applications - Part 209. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Torasemide T 2081 Reference s Kingsbury . et al. J. Med. Chcm. JMCMAR 34 1 98 1991 . EP 321 122 SmithKline Beecham appl. USA-prior. . W09 205 785 SmithKline Beecham appl. USA-prior. . Formulationfs vial 4 mg as hydrochloride Trade Name s D Hycamtin SmithKline GB Hycamtin SmithKline USA Hycamtin SmithKline Beecham F Hycamtin SmithKline I Beecham Beecham Beecham Hycamtin SmithKline Beecham Torasemide AC 4464 BM 02015 Use antihypertensive loop diuretic RN 56211-40-6 MF C16H20N4O3S MW CN A TMethylethyl amino carbonyl -4 3-methylphcnyl amino -3-pyridinesulfonamide sodium salt RN 72810-59-4 MF C16H2oN403S xNa MW unspecified OH pci5 POCIi 4-chloropyridine- 3-sulfanamtde II 4-hydroxy-pyridine m-taluidine HI 3- sulfanomido- 4- 3-methylanilino - pyridine IV CH TEA 95 C IV OCN --------- isopropyl isocyanate V Torasemide TEA 0 I Cl O H H III Cu 95 C ch3 ------------- Torasemide 1 -isopropyl-3- 4-chlor0- 3-pyridylsulfonyl ureo 2082 T Toremifene Reference s a bDelarge J. . ARZNAD 38 I la 1988 . DE 2 516 025 A. Christiaens appl. GB-prior. . stable crystalline modification DE 3 623 620 Boehringer Mannheim appl. D-prior. . injections containing torasemide DE 3 623 620 Boehringer Mannheim D-prior. . rapidly disintegrating pellets WO 09 810 754 Boehringer Mannheim appl. D-prior. . polymorphism and control of the serum solubility of orally administered torasemide US 5 914 336 Boehringer Mannheim USA-prior. . tablets containing torasemide WO 9 300 097 Boehringer Mannheim appl. J-prior. . use for treatment of brain edema DE 4 113 820 Boehringer Mannheim D-prior. . Formulation s amp. mg 2 ml mg 4 ml mg 20 ml as sodium salt tabl mg 5mg 10 mg Trade Name s D Torem Berlin-Chemie Unat Roche 1999 Toremifene ATC L02BA02 FC-1157a Use antiestrogen antineoplastic RN 89778-26-7 MF C26H28C1NO .

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