TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 201

Pharmaceutical Substances Syntheses, Patents, Applications - Part 201. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Tetracycline T 2001 COOH I CH butyl bromide 4-amino- 4-butylamino- HCI --------------- 2-dimethyl-ominoethanol I Tetracaine benzaic acid benzole acid NoOC2H5 -----------k 1. OHC CH 2. H2 Pd-C 1. butyraldehyde 2-dimethylamino-ethyl 4-amino-benzoote Tetrocoine nh2 ethyl 4-omino-benzoate Reference s US 1 889 645 Winthrop 1932 CH-prior. 1930 . Formulation s ear drops 5 mg g in combination preparations eye drops 6 mg g sol. 1 g 100 g spray 5 mg ml 2 as hydrochloride Trade Name s D Acoin Combustinwerk - comb. Gingicain M Spray Hoechst -comb. Herviros Hermal -comb. Ophtocain Winzer -comb. Oto-Flexiole Mann F only combination preparations Amygdospray Merck-Clevenot Broncorinol Manx de gorge Roche Nicholas SA Cantalene RPR Cooper Eludril Inava Hexomedine Theraplix Lysofon L. Laton Oromedine Sanofi Winthrop Otylol Bridoux Solutricine Tetracaine Theraplix SA Tyrcine Oberlin GB Eludril Chefaro -comb. Minims amethocaine Chauvin I only combination preparations Corizzina SIT Donalg Dinacren J Butylcain Tanabe Recto-reparil Naturwaren Madaus Ruscoroid Inverni della Beffa Tetocaine Kyorin USA Cetacaine Cetylite Tetracycline ATC A01AB13 D06AA04 J01AA07 S01AA09 SO2AAO8 S03AA02 Use antibiotic antibacterial antiamebic antitrichettisal RN 60-54-8 MF C22H24N2O8 MW EINECS 200-481-9 LD50 157 mg kg M . 678 mg kg M . 129 mg kg R . 807 mg kg R . CN 4S- 4a 4aa 5aa 6p 12aa -4- dimethylamino -1 4 4a 5 5a 6 11 12a-octahydro-3 6 10 12 12a-pentahydroxy-6-methy 1-1 11 -dioxo-2-naphthacene carboxamide 2002 T Tetracycline monohydrochloride RN 64-75-5 MF C H NjOjr HCl MW EINECS 200-593-8 LD50 157 mg kg M . 2759 mg kg M . 128 mg kg R . 6443 mg kg R . phosphate RN 1336-20-5 MF unspecified MW unspecified E1NECS 215-646-0 H c ohh H Chlortetracycline q. V. from fermentation solutions of Streptomyces viridifociens or aureofociens References a US 2 699 054 L. H. Conover 1955 prior. 1953 . US 3 005 023 American Cyanamid appl. . Boothe . et al. J. Am.

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