TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 63

Pharmaceutical Substances Syntheses, Patents, Applications - Part 63. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Diacerein D 621 synthesis o l-methyl-7-methoxy-2-tetralone Howele . Taylor . J. Chem. Soc. JCSOA9 1958 1248. pharmaceutical formulations US4605 671 American Home appl. prior. . WO 9 000 390 American Home appl. S-prior. . EP180 303 American Home appl. USA-prior. . Formulationfs vial and Tubex syringe 5 mg 2 ml 10 mg 2 ml 15 mg 2 ml Trade Name s USA Dalgan Wyeth-Aycrst 1990 Diacerein ATC M01AX21 Use anti-inflammatory RN 13739-02-1 MF C19H12O8 MW EINECS 237-310-2 LD50 7500 mg kg R route unreported . CN 4 5-bis acetyloxy -9 10-dihydro-9 10-dioxo-2-anthracenecarboxylic acid L8-dihydroxy-3-hydroxymethyl-cnthroqulnone e g. from borboloin 0 0 1 8-dihydroxy-3- Diocerein anthraquinone- --------------------- carboxylic acid Reference s DOS 2 711 493 C. A. Friedmann appl. SA-prior. . Oesterle . Arch. Pharm. Weinheim Ger. ARPMAS 241 604 1903 . Robinson R. Simonsen . J. Chem. Soc. JCSOA9 1909 1085. Cahn . Simonsen . J. Chem. Soc. JCSOA9 1932 2573. Formulation s cps. 50 mg Trade Name s 1 Artrodar Proter Fisiodar Gentili Diazepam ATC N05BA01 Use tranquilizer hypnotic RN 439-14-5 MF C16H13C1N2O MW EINECS 207-122-5 CN 7-chloro-l 3-dihydro-l-methyl-5-phenyl-2 -l 4-benzodiazepin-2-one 622 D Diazepam NaOCH3 ----------------- dimethyl sulfate III 2-amino-5- glycine ethyl ester chlorobenzo- hydrochloride 11 phenone I 7-chlara-2-oxo-5-phenyl-2 3-di-hydra-1 H-1 4-benzodiazepine p toluenesulfonyl chloride Tos-CI 2-methylamino-benzophenone IV chloroacetyl hexamethylenetetramine -----------------------k chloride Diazepam NaNO2 HCI ----------- --------------- ethyl a-benzyl- acetoacetate 4-chloraaniline 4-chlorobenzene-diazonium chloride ethyl 5-chloro-3-phenylindole-2-carbaxylate Diazepam D 623 LiAIH VI ------------ lithium alanate 2- aminomethyl-5-chloro-1 -methyl- 3- phenylindole CrO2 chromium Vl oxide Diazepam Alternatively to the Japp-Klingemann reaction .

• Sinh học
• 2267 hoạt chất dược phẩm
• Sách nghiên cứu dược
• hoạt chất dược phẩm
• tổng hợp quá trình sản xuất
• sáng chế thuốc