TAILIEUCHUNG - Diabetic nephropathy: Time to withhold development and progression - A review

The recent discoveries in the fields of pathogenesis and management of diabetic nephropathy have revolutionized the knowledge about this disease. Little was added to the management of diabetic nephropathy after the introduction of renin angiotensin system blockers. The ineffective role of the renin- angiotensin system blockers in primary prevention of diabetic nephropathy in type 1 diabetes mellitus necessitated the search for other early therapeutic interventions that target alternative pathogenic mechanisms. Among the different classes of oral hypoglycemic agents, recent studies highlighted the distinguished mechanisms of sodium glucose transporter 2 blockers and dipeptidyl peptidase-4 inhibitors that settle their renoprotective actions beyond the hypoglycemic effects. The introduction of antioxidant and anti-inflammatory agents to this field had also added wealth of knowledge. However, many of these agents are still waiting well-designed clinical studies in order to prove their beneficial therapeutic role. The aim of this review of literature is to highlight the recent advances in understanding the pathogenesis, diagnosis, the established and the potential renoprotective therapeutic agents that would prevent the development or the progression of diabetic nephropathy. | Diabetic nephropathy: Time to withhold development and progression - A review

• Y khoa - Dược
• Diabetic nephropathy
• Time to withhold development
• Type 1 diabetes
• Type 2 diabetes
• Diabetic nephropathy
• DPP 4 inhibitors
• Diabetes mellitus
• Gene expressions
• Risk prediction of diabetic nephropathy
• Pro inflammatory cytokine
• Risk factor
• Diabetic patients
• Kidney function
• Prolonged duration
• BMC Biotechnology
• Half life
• Fibroblast growth factor 21
• Endocrine acting hormone
• Treat diabetic nephropathy
• Stem cells
• Mesenchymal stem cells
• Treating diabetic nephropathy
• Gut microbiota
• Renin angiotensin system
• Metabolism dependent pathways
• Microbial organ
• Albumin creatinine ratio
• Circulating microRNA
• Estimated glomerular filtration rate
• DN related miRs
• Fibroblast growth factor 23
• Glomerular hypertrophy
• Biochemical data
• Telomere length
• Transforming growth factor β1
• Polymerase chain reaction
• Pre diabetes
• Proper glucose homeostasis
• Antioxidant property
• SD rat model via maintenance
• BMC Veterinary Research
• Alpha 2u globulin
• Diabetic kidney disease
• Anticancer drugs
• Mesangial expansion
• Type 2 diabetes mellitus
• C peptide
• Proliferative diabetic retinopathy
• Bariatric surgery
• Diabetic
• Edited
• John S
• D
• Chan
• Health
• Sciences
• medicine
• pharmacolocy
• Artery Graft Surgery
• Saphenous Vein
• Graft Disease – State
• Drug Eluting Balloon
• Additional Therapy
• Cell Death Following
• CNS Complications
• Glycated Hemoglobin
• Complex Relationship
• Ultrasound Placenta
• trình bày báo cáo
• tài liệu báo cáo khoa học
• báo cáo y học
• kiến thức y học
• nghiên cứu y học
• BMC Pharmacology and Toxicology
• Glucagon like peptide
• Mesangial cell
• PPAR delta
• BMC Cancer
• Toll like receptor 4
• Novel therapeutic
• Psoralea corylifolia Linn
• Diabetes in childhood
• Pediatric diabetology
• Quality management
• Beta cell function replacement
• Macrovascular disease