TAILIEUCHUNG - Clinical effects of embryos culture at low oxygen concentration

In in-vitro-fertilization, human embryos have been cultured in incubator which are closely monitored level of components including temperature, humidity and especially level of CO2 and O2 concentration. | Journal of military pharmaco-medicine no5-2018 CLINICAL EFFECTS OF EMBRYOS CULTURE IN LOW OXYGEN CONCENTRATION Nguyen Thi Minh*; Nguyen Viet Tien*; Quan Hoang Lam** SUMMARY In in-vitro-fertilization, human embryos have been cultured in incubator which are closely monitored level of components including temperature, humidity and especially level of CO 2 and O2 concentration. Some centers are using 20% O 2 while others apply only 5% O2 and with this low level of O2, IVF outcome is promising. However, there is no evidence about the optimized level of O2 concentration in human embryos culture. Objectives: To compare pregnancy rate, live birth rate between 2 groups is 5% O2 and 20% O2. Methods: This is a randomized clinical trial study among 172 patients who were divided into 2 groups: embryos cultured in 5% and 20% oxygen concentration. Before culture, using FSH to stimulate ovaries. Oocytes retrieval was done after hCG injection 36 hours. Fertilization was made by conventional IVF or ICSI. On day 3, 3 - 5 top quality embryos were selected to culture to day 5 in both groups. Residual embryos were frozen by vitrification method. Results: No differences in characteristics of ovarian reserve, ovarian stimulation and embryos transfer in both groups. Clinical pregnancy rate in 5% oxygen group was , significantly higher than in 20% oxygen group. Live birth rate in 5% oxygen group was , higher than in 20% oxygen group but no significantly. Conclusion: Clinical pregnancy rate on day 5 in 5% oxygen group was higher than that in 20% oxygen group. Live birth rate in 5% oxygen group was higher than in 20% oxygen group but no significantly. * Key words: Pregnancy rate; Live birth rate; Low oxygen concentration in IVF. INTRODUCTION The technique of in-vitro fertilization (IVF) has been increasingly advanced in order to improve the success rate. Many studies in the world state that blastocyst transfer is close to physiology and selected embryos with good .

• Y khoa - Dược
• Pregnancy rate
• Live birth rate
• Low oxygen concentration in IVF
• In vitro fertilization
• Embryo culture
• Predominantly blastocyst
• Pre ovulatory follicle
• Pre ovulatory follicle size
• Pregnancy rate in Murrah buffaloes
• Murrah buffaloes
• Pre ovulatory follicle size on pregnancy rate
• BMC Genomics
• Conception rate
• Heifer conception rate
• Pregnancy per breeding
• Successful pregnancy
• Tạp chí khoa học
• Tạp chí y dược
• Y dược quân sự
• Low oxygen concentration
• Contemporary Obstetric
• Umbilical Cord Blood
• Preeclamptic Pregnancy
• Bioethics in Obstetrics
• multi author book
• clinical and research
• trình bày báo cáo
• tài liệu báo cáo khoa học
• báo cáo thú y
• bệnh ở động vật
• nghiên cứu bệnh thú ý
• Volatile Constituents
• Herbal Medicines
• Gas Chromatography
• Designing Novel Functional
• Chromatography
• Chemical Composition
• Behavioral Tests
• Information Processing
• Cognitive Deficits
• Pregnancy and Child’s
• Child’s Health
• Environmental Electromagnetic
• BMC Women's Health
• Moderate endometriosis
• Severe endometriosis
• Surgical access