TAILIEUCHUNG - Antimicrobial peptides: A potential therapeutic alternative for the treatment of fish diseases

Fish losses from infectious diseases are a significant problem in aquaculture worldwide. However, peptide antibiotics show potent activity against a broad range of pathogens including fish pathogens. | Turk J Biol 26 (2002) 201-207 © TÜB‹TAK Antimicrobial Peptides: A Potential Therapeutic Alternative for the Treatment of Fish Diseases Aliye SARMAfiIK Çanakkale Onsekiz Mart University, Faculty of Fisheries, 17100, Çanakkale - TURKEY Received: Abstract: Fish losses from infectious diseases are a significant problem in aquaculture worldwide. However, peptide antibiotics show potent activity against a broad range of pathogens including fish pathogens. Therefore, the ability of antimicrobial peptides to protect fish against infections caused by fish pathogens clearly shows the potential for utilisation of antimicrobial peptides for the treatment of fish diseases. The strategy of overexpressing the antimicrobial peptide genes in transgenic fish may provide a method of decreasing fish disease problems in aquaculture. Key Words: Antimicrobial peptides, cecropin, fish disease, aquaculture Antimikrobiyal Peptidler: Bal›k Hastal›klar›n›n Tedavisinde Potansiyel Bir Terapötik Alternatifi Özet: Kültür bal›kç›l›¤›nda enfeksiyoz hastal›klar nedeniyle görülen bal›k kay›plar› dünya çap›nda oldukça önemli bir problemdir. Antimikrobiyal peptidler olarak bilinen antibiyotikler bal›k patojenleri dahil pekçok patojen organizmay› etkili olarak öldürebilmektedir. Dolay›s›yla patojenlerin oluflturduklar› enfeksiyonlara karfl› bal›klar, antimikrobiyal peptidlerden yararlan›larak korunabilirler. Bu amaçla antimikrobiyal peptidleri kodlayan genlerin bal›klara transferinin yap›lmas› ile transgenik bal›k üretimi kültür bal›kç›l›¤› s›ras›nda karfl›lafl›lan bal›k hastal›klar›n›n azalt›lmas› aç›s›ndan iyi bir strateji sa¤layabilir. Anahtar Sözcükler: Antimikrobiyal peptidler, cecropin, bal›k hastal›klar›, kültür bal›kç›l›¤› Introduction All muticellular organisms are susceptible to infections because from a microbe’s perspective their tissues are rich sources of nutrients. Therefore, multicellular organisms have developed defense systems to recognize invading microorganisms and .

• Sinh học
• Antimicrobial peptides
• Fish disease
• Therapeutic alternative
• Antimicrobial peptides
• Hyalophora cecropia
• BMC Genetics
• Drosophila melanogaster
• Amyloid β peptides
• Transcription factor FOXO
• Peroxiredoxin 5
• Biochemistry
• molecular Biology
• biological cells
• innate immunity
• cytoplasm
• BMC Genomics
• Feature weighting
• Molecular descriptors
• Multi objective evolutionary algorithm
• Peptide representation
• Antimicrobial resistance
• Antimicrobial peptide
• Deep learning
• Feature fusion
• Organisms against microbes
• scientific reports
• thesis report
• medical report
• medical knowledge
• medical research
• analysis of cytoplasmic
• breast cancer
• medicine
• chemical reaction
• Crystal structure
• medical analysis
• biochemical studies
• BMC Plant Biology
• Plant immunity
• Physcomitrella patens
• Cryptic peptides
• Functionally active proteins
• Intercellular fluid
• Cysteine rich peptides
• Heterologous expression
• Transgenic plants
• Vacuum infiltration
• Data independent acquisition
• Trình bày báo cáo
• tài liệu báo cáo khoa học
• nghiên cứu y học
• báo cáo y học
• kiến thức y học
• Report medicine
• traditional medicine
• Cell penetrating peptides
• Antimicrobial peptide LL 37
• RNA interference
• Scanning tunneling electron microscopy
• Protein bodies
• Pathogen resistance
• Fusarium verticillioides
• Dickeya dadantii
• Oryza sativa
• BMC Musculoskeletal Disorders
• Multiple trauma
• Human beta defensin
• Real time PCR
• Parallel identification
• Signal peptide region
• Journal of Zoology
• Foam nest
• Mass spectrometry
• Protein profiling
• Biosynthesis gene clusters
• Genome mining
• Ribosomally synthesized post translationally modified peptides
• Non ribosomal peptides
• immune system
• Antimicrobial
• biosynthesis
• scientific research
• Equus asinus
• genetics
• Structural biochemistry
• Structural Biology
• tumor cells