TAILIEUCHUNG - Effect of TD0014 on intracavernous pressure elicited with electrical stimulation of the cavernous nerve in male rats

This study aimed to determine the effects of an herbal formula named TD0014 on the electrostimulationinduced erection in a rat model. Eighteen sixteen-week-old male Wistar rats were used. The intracavernous pressure and the arterial blood pressure were simultaneously monitored during cavernous nerve electrical stimulation before and after the administration of TD0014 ( g/kg). | JOURNAL OF MEDICAL RESEARCH EFFECT OF TD0014 ON INTRACAVERNOUS PRESSURE ELICITED WITH ELECTRICAL STIMULATION OF THE CAVERNOUS NERVE IN MALE RATS Mai Phuong Thanh1, Pham Thi Van Anh1, Nguyen Trong Thong1, Nguyen Thi Huong Lien 2 1 Department of Farmacology, Hanoi Medical University, 2Sunstar Joint Stock Company This study aimed to determine the effects of an herbal formula named TD0014 on the electrostimulationinduced erection in a rat model. Eighteen sixteen-week-old male Wistar rats were used. The intracavernous pressure and the arterial blood pressure were simultaneously monitored during cavernous nerve electrical stimulation before and after the administration of TD0014 ( g/kg). Statistical analysis was performed on measurements of maximal intracavernous pressure (MIP), mean arterial blood pressure (MAP) and the MIP/MAP. The administration of TD0014 resulted in a significant increase in the baseline level of intracavernosal pressure (ICP) before stimulation in comparison to the control group (P ) MIP/MAP increased significantly compared with distilled water group and TD0014 group (p ). Thus, in the current study, TD0014 given once before nerve stimulation markedly increased baseline ICP, slightly increased both the MIP and the response time to the stimulus. These results suggested that TD0014 may be beneficial for patients with erectile dysfunction, and can improving the patient's sexual life. JMR 111 E2 (2) - .

TỪ KHÓA LIÊN QUAN
TAILIEUCHUNG - Chia sẻ tài liệu không giới hạn
Địa chỉ : 444 Hoang Hoa Tham, Hanoi, Viet Nam
Website : tailieuchung.com
Email : tailieuchung20@gmail.com
Tailieuchung.com là thư viện tài liệu trực tuyến, nơi chia sẽ trao đổi hàng triệu tài liệu như luận văn đồ án, sách, giáo trình, đề thi.
Chúng tôi không chịu trách nhiệm liên quan đến các vấn đề bản quyền nội dung tài liệu được thành viên tự nguyện đăng tải lên, nếu phát hiện thấy tài liệu xấu hoặc tài liệu có bản quyền xin hãy email cho chúng tôi.
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.