TAILIEUCHUNG - Báo cáo khoa hoc:" Drug-induced hepatitis superimposed on the presence of anti-SLA antibody: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Drug-induced hepatitis superimposed on the presence of anti-SLA antibody: a case report | Journal of Medical Case Reports BioMed Central Case report Open Access Drug-induced hepatitis superimposed on the presence of anti-SLA antibody a case report Aitziber Etxagibel 1 M Rosa Julia2 Alvaro Brotons3 M Margarita Company4 and Carlos Dolz3 Address Department of Family Practice Post-graduate Unit Palma de Mallorca Spain 2Immunology Service Son Dureta Hospital Palma de Mallorca Spain 3Gastroenterology and Hepatology Department Son Llatzer Hospital Palma de Mallorca Spain and 4Pathology Department Son Llatzer Hospital Palma de Mallorca Spain Email Aitziber Etxagibel - aitziberg@ M Rosa Julia - mrjulia@ Alvaro Brotons - abrotons@ M Margarita Company - mcompany@ Carlos Dolz - cdolz@ Corresponding author Published 28 January 2008 Received 23 June 2007 Journal of Medical Case Reports 2008 2 25 doi 86 1752-1947-2-25 Accepted 28 January 2008 This article is available from http content 2 1 25 2008 Etxagibel et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Autoimmune hepatitis is a necroinflammatory disorder of unknown etiology characterized by the presence of circulating antibodies hypergammaglobulinemia and response to immunosuppression. It has the histological features of chronic hepatitis. The onset is usually insidious but in some patients the presentation may be acute and occasionally severe. Certain drugs can induce chronic hepatitis mimicking autoimmune hepatitis. Different autoantibodies have been associated with this process but they are not detectable after drug withdrawal and clinical resolution. Case presentation We describe a case of drug-induced acute hepatitis associated with antinuclear antisoluble liver-pancreas .

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