TAILIEUCHUNG - CIGARETTE SMOKING AND ITS RELATION TO PULMONARY TUBERCULOSIS IN ADULTS

In the Revised National Tuberculosis Control Programme (RNTCP) in India, the target of 85 per cent cure rate has been attained. A recent report indicates a success rate of 87 per cent in 200915. This, however, is a mean of results achieved throughout the country with a HIV prevalence of per cent16. The distribution of HIV infection is uneven and there are six States which have HIV prevalence over 1 per cent. In such areas, the prevalence of HIV infection in TB patients may be high, which could in turn affect the efficacy of the RNTCP regimen. In the TB. | CIGARETTE SMOKING AND ITS RELATION TO PULMONARY TUBERCULOSIS IN ADULTS Niorn Ariyothai1 Amornrath Podhipak2 Pasakorn Akarasewi1 Songpol Tornee3 Saijai Smithtikarn1 and Pittaya Thongprathum1 Tuberculosis Division Ministry of Public Health 2Department of Epidemiology Faculty of Public Health Mahidol University Department of Health Education Srinakarinwirot University Bangkok Thailand Abstract. The purpose of this hospital-based case-control study is to determine the effect of passive and active smoking on pulmonary TB in adults. The study subjects were 100 new pulmonary TB cases diagnosed at TB Division and age-sex matched 100 non-TB cases from patients admitted to Taksin Hospital and healthy subjects who came for annual physical check-up at either the outpatient clinic of the TB division or Taksin Hospital during May 2001 to October 2001. All subjects had blood tests and only persons who were HIV-negative DM-negative and free of other lung diseases were included. Data were collected by direct interview using questionnaires. Multivariate analysis of cigarette smoking related to pulmonary TB in adults was performed. The factors related to pulmonary TB in adults were current active smoking regardless of passive smoking exposure. There was a significant association between early age at initiation of smoking and TB. Active current ex-active smokers who started smoking at age 15-20 years had a higher risk of pulmonary TB compared to others OR 95 CI as well as the long duration of smoking persons who had smoked 10 years had a higher risk of pulmonary TB OR 95 CI . There was a relationship between pulmonary TB and the amount of smoking exposure. Those who smoked 10 cigarettes day OR 95 CI or 3 days week Or 95 CI had higher risk of pulmonary TB compared to non-smokers. Passive smokers who were exposed to tobacco smoke 3 times week outside the home had a higher risk of pulmonary TB than those with exposure 3 times .

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