TAILIEUCHUNG - Báo cáo khoa học: From meiosis to postmeiotic events: Alignment and recognition of homologous chromosomes in meiosis

Recombination of homologous chromosomes is essential for correct reduc-tional segregation of homologous chromosomes, which characterizes meio-sis. To accomplish homologous recombination, chromosomes must find their homologous partners and pair with them within the spatial con-straints of the nucleus. | MINIREVIEW From meiosis to postmeiotic events Alignment and recognition of homologous chromosomes in meiosis Da-Qiao Ding1 Tokuko Haraguchi1 2 3 and Yasushi Hiraoka1 2 3 1 Kobe Advanced ICT Research Center National institute of Information and Communications Technology Kobe Japan 2 Graduate Schoolof Frontier Biosciences Osaka University Suita Japan 3 Department of Biology Graduate Schoolof Science Osaka University Toyonaka Japan Keywords bouquet arrangement double-strand break homologous chromosome pairing KASH domain protein meiosis recombination SUN domain protein synaptonemal complex telomere transcription Correspondence Y. Hiraoka Graduate Schoolof Frontier Biosciences Osaka University 1-3 Yamadaoka Suita Japan Fax 81 6 6879 4622 Tel 81 6 6879 4620 E-mail hiraoka@ Recombination of homologous chromosomes is essential for correct reduc-tional segregation of homologous chromosomes which characterizes meio-sis. To accomplish homologous recombination chromosomes must find their homologous partners and pair with them within the spatial constraints of the nucleus. Although various mechanisms have developed in different organisms two major steps are involved in the process of pairing first alignment of homologous chromosomes to bring them close to each other for recognition and second recognition of the homologous partner of each chromosome so that they can form an intimate pair. Here we discuss the various mechanisms used for alignment and recognition of homologous chromosomes in meiosis. Received 10 August 2009 revised 21 October 2009 accepted 5 November 2009 doi Introduction Meiosis is an essential process for sexually reproducing eukaryotic organisms producing haploid gametes or spores from a diploid cell. In this process one round of DNA replication is followed by two consecutive nuclear divisions to halve the number of chromosomes. A characteristic feature of meiosis is the behavior exhibited by homologous .

TỪ KHÓA LIÊN QUAN
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.