TAILIEUCHUNG - báo cáo khoa học: "Four year experience of sarcoma of soft tissues and bones in a tertiary care hospital and review of literature"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Four year experience of sarcoma of soft tissues and bones in a tertiary care hospital and review of literature | Ansari et al. World Journal of Surgical Oncology 2011 9 51 http content 9 1 51 5 2 WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access Four year experience of sarcoma of soft tissues and bones in a tertiary care hospital and review of literature 1 11 1 2 3 Tayyaba Z Ansari Nehal Masood Asra Parekh Rabab Z Jafri Syed N Niamatullah Adnan A Zaidi and Masood Umer1 Abstract Background Sarcoma encompasses an uncommon group of cancer and the data is insufficient from Pakistan. We report our four years experience of Sarcoma of soft tissues and bones. Methods This cross sectional study was carried out at Aga Khan University Hospital from 2004 to 2008. The patients were divided into two groups from the outset . initially diagnosed and relapsed group and separate sub group analysis was conducted. Results Out of 93 newly diagnosed patients 58 belonged to bone sarcoma and 35 to soft tissue sarcoma group. While for relapsed patients 5 had soft tissue sarcoma and 9 had bone sarcoma. Mean age was years. At presentation approximately two third patients had localised disease while remaining one third had metastatic disease. The Kaplan Meier estimate of median recurrence free survival was 25 months 35 months and 44 months for Osteogenic sarcoma Ewing s sarcoma and Chondrosarcoma respectively. For Leiomyosarcoma and Synovial sarcoma it was 20 and 19 months respectively. The grade of the tumour p and surgical margin status p were statistically significant for determination of relapse of disease. Conclusion The median recurrence free survival of patients in our study was comparable to the reported literature but with significant lost to follow rate. Further large-scale multi centre studies are needed to have a more comprehensive understanding of this heterogeneous disease in our population. Background The skeleton and soft tissue comprise approximately 75 of the average body weight but the cancer arising from these parts represent 1 of adult and 15 of

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