TAILIEUCHUNG - Chromosomal Instability and Aging Basic Science and Clinical Implications

Understanding the biological basis of aging has fascinated people throughout recorded history, and is one of the great remaining scientific questions. The question has never been more important than now, as we anticipate the impact that a rapidly growing older population will have on the social, political, and medical landscape over the next 50 years. There is increasing evidence that aging involves damage to the genome, and it is certainly the case that such damage explains much of the coupling of most cancers to aging. This volume brings together expert reviews on issues related to the role of chromosomal instability in the modulation of life span and health. | Chromosomal Instability and Aging Basic Science and Clinical Implications edited by Fuki M. Hisama Sherman M. Weissman George M. Martin Chromosomal Instability and Aging Basic Science and Clinical Implications edited by Fuki M. Hisama Sherman M. Weissman Yale University School of Medicine New Haven Connecticut . George M. Martin University of Washington Seattle Washington . M ARCE L Marcel Dekker Inc. DEKKER New York Basel Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress. ISBN 0-8247-0856-3 This book is printed on acid-free paper. Headquarters Marcel Dekker Inc. 270 Madison Avenue New York NY 10016 tel 212-696-9000 fax 212-685-4540 Eastern Hemisphere Distribution Marcel Dekker AG Hutgasse 4 Postfach 812 CH-4001 Basel Switzerland tel 4i-61-260-6300 fax 41-61-260-6333 World Wide Web http The publisher offers discounts on this book when ordered in bulk quantities. For more information write to Special Sales Professional Marketing at the headquarters address above. Copyright 2003 by Marcel Dekker Inc. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means electronic or mechanical including photocopying microfilming and recording or by any information storage and retrieval system without permission in writing from the publisher. Current printing last digit 10 987 6 54321 PRINTED IN THE UNITED STATES OF .

• Y học thường thức
• Xeroderma Pigmentosum
• Model Organisms
• Caenorhabditis elegans
• Oxidative Stress
• Werner syndrome
• Khô da sắc tố
• bệnh Xeroderma Pigmentosum
• bài giảng bệnh học
• bệnh da liễu
• bệnh về da
• giáo trình bệnh da liễu
• BMC Cancer
• DNA damage response
• DNA damaged binding protein 2
• Global genome nucleotide excision repair
• Xeroderma Pigmentosum group G
• RNA polymerase II
• BMC Molecular and Cell Biology
• Werner syndrome protein
• NXF1 export receptor
• Macromolecular synthesis