TAILIEUCHUNG - Kumar et al. Journal of Orthopaedic Surgery and Research 2010, 5:52

Kumar et al. Journal of Orthopaedic Surgery and Research 2010, 5:52 CASE REPORT Open Access Osteoblastoma-like Osteosarcoma of the Cuboid: A Case Report Navin L Kumar1*, Andrew E Rosenberg1,2, Kevin A Raskin1,3 Abstract Osteosarcoma most commonly arises in the long bones of the skeleton, and rarely develops in the bones of the foot. We describe a patient who presented with left foot pain, whose radiographic evaluation revealed a lytic destructive mass in the cuboid bone. A biopsy showed an osteoblastoma-like variant of osteosarcoma and the patient was treated with preoperative chemotherapy and amputation. Osteosarcoma of the foot is uncommon and the literature reveals that. | Kumar et al. Journal of Orthopaedic Surgery and Research 2010 5 52 http content 5 1 52 JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH CASE REPORT Open Access Osteoblastoma-like Osteosarcoma of the Cuboid A Case Report Navin L Kumar1 Andrew E Rosenberg1 2 Kevin A Raskin1 3 Abstract Osteosarcoma most commonly arises in the long bones of the skeleton and rarely develops in the bones of the foot. We describe a patient who presented with left foot pain whose radiographic evaluation revealed a lytic destructive mass in the cuboid bone. A biopsy showed an osteoblastoma-like variant of osteosarcoma and the patient was treated with preoperative chemotherapy and amputation. Osteosarcoma of the foot is uncommon and the literature reveals that it is often associated with a delay in diagnosis. Background Osteosarcoma is a malignant neoplasm of bone in which tumor cells produce neoplastic bone matrix 1 . It is the most common sarcoma of bone and follows multiple myeloma as the second most common primary malignancy of the skeleton 2 . Osteosarcoma usually affects patients in the late teenage years and predominantly originates in the long bones particularly around the knee 1 . Rarely osteosarcoma develops in the bones of the foot 3 . This case report describes a patient who was found to have osteosarcoma of the cuboid bone after developing pain and swelling of his left foot. Although initial diagnostic tests suggested that the lesion was benign an open biopsy revealed a high grade osteoblastoma-like variant of osteosarcoma which to our knowledge is the first case published involving the cuboid bone. Case Presentation Case Report A 32 year old man presented to an outside hospital with a one month history of left foot pain. He recalled that the pain started after he had twisted his ankle during a round of golf. Since that time the pain had persisted and was most severe along the lateral aspect of his left foot. On physical examination there was moderate swelling .

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