TAILIEUCHUNG - The National Cancer Institute's Thésaurus and Ontology

Countless organizations have their own intricate and well-developed thesauri that have been refined over many years. With consummate converters, these thesauri can become a strong and useful element on the semantic web. Like the Thésaurus from the National Cancer Institute, many are available in an unusual form of XML, or not in XML at all. As in this case, simple translations using standard XML parsers often will not be a reasonable solution for making the transition to RDF or OWL. The most time. | The National Cancer Institute s Thesaurus and Ontology Jennifer Golbeck1 Gilberto Fragoso2 Frank Hartel2 Jim Hendler1 Jim Oberthaler2 Bijan Parsia1 University of Maryland College Park 2National Cancer Institute Center for Bioinformatics golbeck@ fragosog@ hartel@ hendler@ bparsia@ oberthaj@ Introduction The NCI Thesaurus is a public domain description logic-based terminology produced by the National Cancer Institute and distributed as a component of the NCI Center for Bioinformatics caCORE distribution 1 . It is deep and complex compared to most broad clinical vocabularies implementing rich semantic interrelationships between the nodes of its taxonomies. The semantic relationships in the Thesaurus are intended to facilitate translational research and to support the bioinformatics infrastructure of the Institute. The NCI Thesaurus evolved from the NCI Metathesaurus. NCI Metathesaurus is based on the National Library of Medicine Unified Medical Language System UMLS Metathesaurus. The NCI Metathesaurus has been operational since 1999. A public version is available at http . The need for a comprehensive NCI-wide terminology arose because NCI staff requires access to timely and accurate information about activities related to the scientific mission of the Institute. The collection storage and retrieval of data related to NCI research programs is necessary to analyze manage and report about these activities. Though centralized coding of NCI-supported research-related activities met some of these needs supplementary data coding had become common. This coding was assigned independently within various components of the Institute and was frequently based on locally developed term lists or other informal vocabulary making it difficult to find and combine information across programs. The NCI source vocabulary within the NCI Metathesaurus encompasses the terminology used by the various offices

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