TAILIEUCHUNG - Chapter 118. Infective Endocarditis (Part 14)

Antibiotic prophylaxis, if 100% effective, likely prevents only a small number of cases of endocarditis; nevertheless, it is possible that rare cases are prevented. Weighing the potential benefits, potential adverse events, and costs associated with antibiotic prophylaxis, the expert committee of the American Heart Association has dramatically restricted the recommendations for antibiotic prophylaxis. Prophylactic antibiotics (Table 118-7) are advised only for those patients at highest risk for severe morbidity or death from endocarditis (Table 1188). Prophylaxis is recommended only for dental procedures wherein there is manipulation of gingival tissue or the periapical region of the teeth or perforation of. | Chapter 118. Infective Endocarditis Part 14 Antibiotic prophylaxis if 100 effective likely prevents only a small number of cases of endocarditis nevertheless it is possible that rare cases are prevented. Weighing the potential benefits potential adverse events and costs associated with antibiotic prophylaxis the expert committee of the American Heart Association has dramatically restricted the recommendations for antibiotic prophylaxis. Prophylactic antibiotics Table 118-7 are advised only for those patients at highest risk for severe morbidity or death from endocarditis Table 1188 . Prophylaxis is recommended only for dental procedures wherein there is manipulation of gingival tissue or the periapical region of the teeth or perforation of the oral mucosa including surgery on the respiratory tract . Although prophylaxis is not advised for patients undergoing gastrointestinal or genitourinary tract procedures it is recommended that effective treatment be given to these highrisk patients before or when they undergo procedures on an infected genitourinary tract or on infected skin and related soft tissue. Maintaining good dental hygiene is also advised. For further details see http www. americanheart. org identifier 3047083. Table 118-7 Antibiotic Regimens for Prophylaxis of Endocarditis in Adults with High-Risk Cardiac Lesions0 A. Standard oral regimen 1. Amoxicillin g PO 1 h before procedure B. Inability to take oral medication 1. Ampicillin g IV or IM within 1 h before procedure C. Penicillin allergy 1. Clarithromycin or azithromycin 500 mg PO 1 h before procedure 2. Cephalexinc g PO 1 h before procedure 3. Clindamycin 600 mg PO 1 h before procedure D. Penicillin allergy inability to take oral medication 1. Cefazolinc or ceftriaxonec g IV or IM 30 min before procedure 2. Clindamycin 600 mg IV or IM 1 h before procedure Dosing for children for amoxicillin ampicillin cephalexin or cefadroxil use 50 mg kg PO cefazolin 25 mg kg IV .

• Y học thường thức
• Infective Endocarditis
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu học ngành y
• Harrisons Internal Medicine
• BMC Veterinary Research
• Aortic valve
• Erysipelothrix rhusiopathiae
• Cardiac arrhythmias
• Significant regurgitation
• Non bacterial thrombotic endocarditis
• Lung cancer
• Deep vein thrombosis
• Transthoracic echocardiogram
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