TAILIEUCHUNG - Báo cáo sinh học: " Autosomal recessive myotonia in sheep"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Autosomal recessive myotonia in sheep | Genet Sei Evol 1997 29 291-294 Elsevier Inra 291 Original article Autosomal recessive myotonia congenita in sheep GA Moore1 KR Dyer2 RM Dyer3 DP Sponenberg4 1 Department of Large Animal Clinical Sciences 2 Department of Small Animal Clinical Sciences 3 Department of Clinical Sciences Maryland 4 Department of BioSciences and Pathobiology Virginia-Maryland Regional College of Veterinary Medicine Virginia Polytechnic Institute and State University Blacksburg VA 24061 USA Received 6 August 1996 accepted 10 March 1997 Summary - Myotonia congenita in sheep causes episodes of muscular rigor following various stimuli. Episodes are transitory and do not harm the animal. Incidence in the flock of origin included three ewe lambs and three ram lambs. Two of the affected animals resulted from the mating of one specific unaffected ram to the unaffected daughters of a second unaffected ram. This mating produced 25 normal animals in addition to the two myotonic animals which is consistent with the hypothesis of an autosomal recessive gene responsible for the condition assuming the sire and maternal grandsire were the only ancestors carrying the gene y2 1 df p . The four other affected animals had these two introduced rams in their pedigrees on both maternal and paternal sides suggesting that these two rams might indeed have introduced the gene into this flock. sheep myotonia congenita genetics Resume Myotonie congénitale autosomale recessive chez le mouton. La myotonie congenitale chez le mouton cause des episodes de raideur musculaire suite à divers stimuli. Ces episodes sont passagers et ne sont pas nuisibles à I animal. Elie concemait trois agneaux males et trots agneaux femelies dans le troupeau d origine. Deux des animaux affectes résultaient de raccouplement d un belter non affecte avec les filles non affectees d un second belter non affecte. Get accouplement a produit 25 animaux normaux en plus des animavx myotoniques ce qui est coherent avec I hypothese d un gene

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