TAILIEUCHUNG - Báo cáo khoa hoc:"Food resource allocation patterns in lactating females in a long-term selection experiment for litter size in mice"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Food resource allocation patterns in lactating females in a long-term selection experiment for litter size in mice | 83 Genet Sei. Evol. 34 2002 83-104 INRA EDP Sciences 2002 DOI gse 2001005 Original article Food resource allocation patterns in lactating females in a long-term selection experiment for litter size in mice WendY M. Rauwa Pieter w. Knapb Martinus . Verstegenc Petronella Luitingb a Area de Producció Animal Centre UdL-IRTA Alcalde Rovira Roure 177 25198 Lleida Spain b PIC Deutschland GmbH . Box 1630 D-24826 Schleswig Germany c Animal Nutrition Group Wageningen Institute of Animal Science . Box 338 6700 AH Wageningen The Netherlands Received 14 June 2000 accepted 25 July 2001 Abstract - Resource allocation patterns as quantified by residual food intake RFI and the consequences for offspring development were investigated during lactation in 96 females of a mouse line selected for 104 generations for high litter size at birth S-line and in 87 females of a non-selected control line C-line . Litters of 45 C-line dams Cs and 48 S-line dams Ss were standardised s at birth other dams ns supported total number of pups born Cns and Sns respectively . RFI during lactation was significantly lower in Sns-dams than in C-line dams and Sns-dams. After weaning Sns-dams seemed to be able to restore the negative resource situation. Sns-pups were about 25 less mature than Cns-pups at all times. Maturity was similar for Cs- and Ss-pups from 2 d in lactation on and about 18 and 53 higher than Cns- and Sns-pups. The pre-weaning mortality rate was significantly higher in Sns-litters than in Cns-litters . The results suggest that S-line dams allocated considerably more resources to maintenance of offspring than C-line dams. This was insufficient to provide the offspring with an adequate amount of resources resulting in reduced pup development and increased pre-weaning mortality rates. mice litter size lactation resource allocation residual food intake 1. introduction Residual food intake is defined as the part of food intake that is unaccounted for by food

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