TAILIEUCHUNG - Báo cáo sinh học: "Analysis of the human cytomegalovirus genomic region from UL146 through UL147A reveals sequence hypervariability, genotypic stability, and overlapping transcripts"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Analysis of the human cytomegalovirus genomic region from UL146 through UL147A reveals sequence hypervariability, genotypic stability, and overlapping transcripts | BioMed Central Virology Journal Research Open Access Analysis of the human cytomegalovirus genomic region from UL146 through UL147A reveals sequence hypervariability genotypic stability and overlapping transcripts Nell S Lurain 1 Andrea M Fox1 Heather M Lichy2 3 Sangeeta M Bhorade4 Carl F Ware5 Diana D Huang1 Sau-Ping Kwan1 Edward R Garrity3 and Sunwen Chou2 3 Address Department of Immunology Microbiology Rush University Medical Center Chicago IL USA 2Medical and Research Services VA Medical Center Portland OR USA 3Division of Infectious Diseases Oregon Health Science University Portland OR USA 4Division of Pulmonary and Critical Care Loyola University Medical Center Maywood IL USA and 5Division of Molecular Immunology La Jolla Institute for Allergy and Immunology San Diego CA USA Email Nell S Lurain - nlurain@ Andrea M Fox - andrea_m_fox@ Heather M Lichy - fohlh@ Sangeeta M Bhorade - sbhorad@ Carl F Ware - cware@ Diana D Huang - diana_huang@ Sau-Ping Kwan - sau-ping_kwan@ Edward R Garrity - egarrit@ Sunwen Chou - chous@ Corresponding author Published 12 January 2006 Received 31 August 2005 Accepted 12 January 2006 Virology Journal 2006 3 4 doi 86 I743-422X-3-4 This article is available from http content 3 1 4 2006 Lurain et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Although the sequence of the human cytomegalovirus HCMV genome is generally conserved among unrelated clinical strains some open reading frames ORFs are highly variable. UL146 and UL147 which encode CXC chemokine homologues are among these variable ORFs. Results The region of the HCMV genome from UL146 through UL147A was analyzed in .

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