TAILIEUCHUNG - NEW INSIGHTS INTO TOXICITY AND DRUG TESTING

This book "New Insights into Toxicity and Drug Testing" covers all emerging technologies (profiling technologies, 3D cultures, next generation sequencing etc.), available methods and models to evaluate candidate drugs and medicinal plants with reference to toxicity, drug testing and development. This book is an original contribution of experts from different parts of the globe and the in-depth information will be a significant resource for scientists and physicians who are directly dealing with drugs / medicines and human life | NEW INSIGHTS INTO TOXICITY AND DRUG TESTING Edited by Sivakumar Gowder New Insights into Toxicity and Drug Testing http 55886 Edited by Sivakumar Gowder Contributors Ifeoma Obidike Azad Mohammed Michaela Reddy Harvey Clewell Thierry Lave Melvin Andersen Ray Greek Abdelmigid Nasir Mohamad Peter Ward David La J. Eric McDuffie Sandra Snook Elsa Dias Carina Menezes Elisabete Valério Jose M Fuentes Jacob John Van Tonder Mary Gulumian Vanessa Steenkamp Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2013 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Ana Pantar Technical Editor InTech DTP team Cover InTech Design team First published January 2013 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ New Insights into Toxicity and Drug Testing Edited by Sivakumar Gowder p. cm. ISBN 978-953-51-0946-4 INTECH open .

• Y học thường thức
• Candidate Drugs
• Toxicity of Microcystins
• Herbal Medicines
• Potential Toxicities
• Animal Models
• Drug Development
• BMC Bioinformatics
• Drug repositioning
• Drug discovery
• Multi omics
• BMC Pharmacology and Toxicology
• Despite the multitude
• Intestinal absorption
• Selecting candidate drugs
• Quantitative structure activity relationship
• of Drug Metabolism
• Drug Metabolite
• Quantitative Drug Metabolism
• Development Processes
• Drug Metabolism
• Medicinal Chemistry
• Drug target relations
• Compound protein relations
• Drug repositioning
• Biological effect
• Molecular histopathology
• Tissue biomarkers in drug
• Diagnostic development
• Final recommendations
• Three companion diagnostic development paths
• Companion diagnostics
• Development of solidified self microemulsifying drug delivery systems containing L tetrahydropalmatine
• Design of experiment approach and bioavailability comparison
• Solidified self microemulsifying drug delivery systems containing L tetrahydropalmatine
• Pellet SMEDDS in the rabbit model
• Cardiovascular pharmacotherapeutics
• Complementarymedicine for preventing
• Treatingcardiovascular disease
• Cardiovascular drug–drug interactions
• Drug treatment of peripheral vascular disorders
• Cardiovascular drugs in development
• Pediatric cardiovascular pharmacology
• Carbohydrate polymers
• Pulmonary drug delivery
• Biodegradable polymer
• Biocompatible polymer
• Drug carrier
• Natural products
• Microbial biocatalysts
• Pharmaceutical products
• Microbial biotransformation
• Drug development based
• Natural products from mevalonic acid pathway
• BMC Musculoskeletal Disorders
• Synovial biopsy
• Rheumatoid arthritis
• Signalling pathways
• Joint deformity
• Principles of pharmacology
• The pathophysiologic basis of drug therapy
• Principles of chemotherapy
• Environmental toxicology
• Frontiers in pharmacology
• Fundamentals of drug development
• Embryonic development
• Zinc chloride
• Zebrafish embryos
• Drug development technologies
• Early life stage
• Polysaccharides for Colon
• Targeted Drug Delivery
• Improved Drug
• Release Specificity
• Therapeutic Benefits
• Factors in Pathogenesis
• RNA interference
• model organisms
• Mucor ciccinelloides
• functional genomics
• human genome
• Illustrated pharmacology for nurse
• Classification and nomenclature of drugs
• Pharmacodynamics of drugs
• Pharmacokinetics of drugs
• Adverse effects of drugs
• Drug interactions
• Artemisinin based combination therapy
• Drug resistance
• Sub Saharan Africa
• World Health Organization
• Precision medicine
• Gene regulatory networks
• Biochemical pathways
• Active learning
• Machine learning
• Computational biology
• Materials and methods
• Heterogeneity approaches
• Image analysis tools
• Histopathology in mouse models
• Quantification of blood
• inclusive
• comprehensive and ratifiable
• climate change
• inefficient resource
• society organizations
• Environment and Development
• Cytochrome P450
• Interleukin 6
• Monoclonal antibody
• Therapeutic protein–drug interaction
• Multiple cytochrome P450 enzymes
• High performance liquid chromatography
• Drug excipient compatibility
• PDA detector
• Analytical wavelength
• Intermediate precision
• Pluronic – grafted copolymers
• Grafted copolymers as nanoplatforms
• Effectively delivering hydrophobic anticancer drugs
• Innovative development
• Development of an elaa kit to detect neomycin in milk
• Detect neomycin in milk
• Enzyme linked aptamer assay
• Method a variant of ELISA
• Drug resistant infection outbreaks
• capillary electrophoresis
• dodecylcarboxylic acid
• cyclic votammetry
• extrusion technique
• glycerol monooleate
• optical density
• Binding Proteins
• Posttranscriptional Networks
• Biological Macromolecules
• mRNA Stability
• Parasitic Protozoa