TAILIEUCHUNG - Alkaloids - Secrets of Life: Aklaloid Chemistry, Biological Significance, Applications and Ecological Role

This book is intended to be a presentation of alkaloids from chemical, biological and ecological points of view. It is a text for chemists, biologists and ecologists alike. However, the intended audience of this work is not limited to scientists, teachers and other present and future specialists. In fact, I wrote this book because I felt the need for it as a university educator and as a scientific enthusiast on the subject. My purpose was to compose a beneficial text for an academic and professional audience that could also serve as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. As. | List of Figures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 Contemporary scheme of morphine. 2 Some alkaloids isolated by pharmaceutists Pierre Joseph Pelletier and Joseph Beinamé Caventou during 1817-1821. 3 Schemes of taxol vinblastine vincristine and vincamine 5 An example of a true alkaloid 11 An example of protoalkaloids 11 An example of a pseudoalkaloid 12 The raw extraction of quinolizidine alkaloids 13 L-tryptophan with its aromatic side chain 15 The devil s-pepper genus Rauwolfia serpentina 15 L-phenylalanine is a precursor 17 L-ornithine is an important precursor 19 L-tyrosine with its aromatic side chain 19 L-anthranilic acid is a precursor 23 L-histidine is a precursor 24 L-ornithine and L-nicotinic acids are precursors 26 L-lysine is a precursor 31 a Structure of seed testa of the Washington lupine b Alkaloidal Lupinus polyphyllus Lindl. 32 Jervine cyclopamine and protoveratrine structures. 49 Basic alkaloids of mushrooms. 55 Ergotamine and LSD 56 Secondary metabolism blocks 65 Pyruvate derivation and acetyl CoA synthesis 66 General scheme of alkaloid synthesis 68 L-lysine-derived nuclei 69 Nuclei and skeletons of izidine alkaloids 70 The source and forms of the pyrrolidine ring 70 L-histidine and the nuclei of imidazole and manzamine alkaloids. 70 The nuclei produced by anthranilic acid in alkaloids 71 The nucleus of alkaloids derived from nicotinic acid 72 L-phenylanine-derived nuclei in alkaloid biosynthesis 72 Nuclei supplied to alkaloids by L-tyrosine in the synthesizing process 73 The L-tryptophan-supplied nucleus during synthesis 74 Synthesis of alkaloids from ornithine 75 Synthesis pathway of the pyrrolizidine alkaloids 76 Synthesis of hordeine and mescaline 77 xii 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73. 74 75 76 77 78 79 80 List of Figures Synthesis pathway of kreysigine and colchicine 77 Emetine and cephaeline .

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