TAILIEUCHUNG - Chapter 057. Photosensitivity and Other Reactions to Light (Part 8)

Natural photoprotection is provided by structural proteins in the epidermis, particularly keratins and melanin. The amount of melanin and its distribution in cells is genetically regulated, and individuals of darker complexion (skin types IV–VI) are at decreased risk for the development of acute sunburn and cutaneous malignancy. Other forms of photoprotection include clothing and sunscreens. Clothing constructed of tightly woven sun-protective fabrics, irrespective of color, affords substantial protection. Wide-brimmed hats, long sleeves, and trousers all reduce direct exposure. Sunscreens are now considered to be over-the-counter drugs and category I ingredients are recognized by the . Food and Drug Administration (FDA). | Chapter 057. Photosensitivity and Other Reactions to Light Part 8 Natural photoprotection is provided by structural proteins in the epidermis particularly keratins and melanin. The amount of melanin and its distribution in cells is genetically regulated and individuals of darker complexion skin types IV-VI are at decreased risk for the development of acute sunburn and cutaneous malignancy. Other forms of photoprotection include clothing and sunscreens. Clothing constructed of tightly woven sun-protective fabrics irrespective of color affords substantial protection. Wide-brimmed hats long sleeves and trousers all reduce direct exposure. Sunscreens are now considered to be over-the-counter drugs and category I ingredients are recognized by the . Food and Drug Administration FDA as monographed and safe and effective. These are listed in Table 57-5. Sunscreens are rated for their photoprotective effect by their SPF. The SPF is simply a ratio of the time required to produce sunburn erythema with and without sunscreen application. The monograph stipulates that sunscreens must be rated on a scale ranging from minimal SPF 2 and 12 to moderate SPF 12 and 30 to high SPF 30 labeled as 30 . No SPF number 30 can be placed on the label. Table 57-5 FDA Category 1 Monographed Sunscreen Ingredients Ingredients Maximum Concentration p-Aminobenzoic acid PABA 15 Avobenzone 3 Cinoxate 3 Dioxybenzone benzophenone-8 3 Ecamsule 15 Homosalate 15 Menthyl anthranilate 5 Octocrylene 10 Octyl methoxycinnamate Octyl salicylate 5 Oxybenzone benzophenone-3 6 Padimate O octyl dimethyl PABA 8 Phenylbenzimidazole sulfonic acid 4 Sulisobenzone benzophenone-4 10 Titanium dioxide .

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