TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 100

Pharmaceutical Substances Syntheses, Patents, Applications - Part 100. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Gusperimus trihydrochloride G 991 2. Pd-C NiCI2 NaBH4 3. HCI X ---------------------------------- 1. dicyclohexylcarbodiimide 0 NH 7-guanidinoheptanamide hydrochloride XI final product 1. HOOC COOH H20 60 C 2. chromatography an sephodex LH-20 XI V -------------------- 1. glutaric acid H OH 0 NH H o H H 2 O 3 HCI Gusperimus trihydrochloride s DE 3 626 306 Microbiochemical Research Found. appl. D-prior. . BE 894 651 Microbiochemical Research Found. appl. J-prior. . JP 08 020 533 Nippon Kayaku appl. J-prior. . DE 3 506 330 Takara Skuzo Co. Nippon Kayaku Co. appl. J-prior. . purification JP 59 029 652 Nippon Kayaku Co. appl. J-prior. . pharmaceutical preparations JP02009 816 Nippon Kayaku Co. Takara Skuzo Co. appl. J-prior. . EP 188 821 Microbial Chemistry Research Found. appl. J-prior. . use of gusperimus hydrochloride CA 2 142 376 Bristol-Myers Squibb Co. appl. USA-prior. . WO9 405 323 Jekus Hopkins Univ. School of Medicine appl. WO-prior. . DE 3 626 306 Behringwerke . appl. D-prior. . synthesis of 0-tert-butyl S - 4 6-dimethyl-2 pyrimidinyl thiocarbonate and O-benzyl 5- 4 6-dimethyl-2- pyrimidinyl thiocarbonate Nagasawaetal. Bull. Chem. Soc. Jpn. BCSJA8 46 1269 1271 1973 . DE 2 245 392 Nitto Boseki appl. J-prior. . US 3 936 452 Nitto Boseki appl. J-prior. . Formulation s vial inj. 100 mg as trihydrochloride Trade Name s J Spanidin Nippon Kayaku 992 H Halazone Halazone Aseptamide ATC D08A Use antiseptic chemotherapeutic RN 80-13-7 MF C7H5C12NO4S MW EINECS 201-253-1 CN 4- dichloroamino sulfonyl benzoic acid sodium salt RN 5698-56-6 MF C7H4Cl2NNaO4S MW EINECS 227-176-3 COOH 0 s o I nh2 4-sulfamoyl-benzoic ocid COOH 0 S 0 I cK ci Halozone Reference s DE 318 899 M. Claass appl. 1918 .

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