TAILIEUCHUNG - Drug Abuse Handbook P2

Clandestine laboratory synthesis of 3,4-methylenedioxyamphetamine (MDA). was significant because here the modification involved the addition of a hydroxyl group as opposed to an alkyl substitution on the nitrogen. Clandestine laboratory synthesis of MDA and MDMA are shown in Figures and The identification of the phenethylamines in the laboratory | Figure Clandestine laboratory synthesis of phenyl-2-propanone p-2-p . Benzyichloride Methylamine Acetaldehyde Figure Clandestine laboratory synthesis of methamphetamine. ch3nh2 Methylamine Benzylmagnesiumchloride vogue and was known then and is still referred to as Ecstasy . The synthesis of 3 4-methylenedioxymethamphetamine MDMA follows the same synthetic protocols as the less complicated phenethylamines. The clandestine laboratory operator or research chemist selectively adds one N-methy group an N N-dimethyl group an N-ethyl group an N-propyl an N-isopropyl group and so on. In 1985 the N-hydroxy MDA derivative was This 1998 by CRC Press LLC 2 5-DIMETH0XY-4-ETHYLAMPHETAMINE 2 5-DIMETHOXY-4-METHYLAMPHETAMINE 3-HYDR0XY-4-METHYL- -ETHYLPHENETHYLAMINE METHOXYPHENAMINE 2- p -CHLOROPHENYL -ETHYLAMINE Figure Clandestine laboratory synthesis of 3 4-methylenedioxyamphetamine MDA . was significant because here the modification involved the addition of a hydroxyl group as opposed to an alkyl substitution on the nitrogen. Clandestine laboratory synthesis of MDA and MDMA are shown in Figures and The identification of the phenethylamines in the laboratory requires great care because of the chemical and molecular similarities of the exhibits. IR combined with MS and NMR 1998 by CRC Press LLC Figure Clandestine laboratory synthesis of 3 4-methylenedioxymethamphetamine MDMA spectrometry provide the most specificity in the identifications of phenethylamines in the forensic science 16 From a legal perspective the laboratory identification of the phenethylamine is Part 1 in the forensic process. If prosecution is an option and the phenethylamine in question is not specified as a controlled substance under Public Law 91-51317 or Part 1308 of the Code of Federal Regulations another legal option is available. In 1986 the . Congress realized that the legal system was at a standstill in attempting to prosecute .

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