TAILIEUCHUNG - Gastritis and peptic ulcer diseases in dogs: A review

The most common clinical condition reported in dogs is acid related diseases in the stomach like gastric disorders due to a structural and functional defect in gastric mucosa. The most important factor for the development of gastritis, peptic ulcer disease and gastric cancer in human is Helicobacter pylori. In the cases of gastric disorder lesions in canine gastric mucosa is closely similar to their human counterparts. Many etiological factors are responsible for oxidative stress due to excessive generation of reactive oxygen species as a cause of gastric mucosal damage. | 2018 7 3 2475-2501 EXCELLENT PUBLISHERS International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 7 Number 03 2018 Journal homepage http Review Article https Gastritis and Peptic Ulcer Diseases in Dogs A Review PqiiLoÌ TCiimỉìv Poffi 1 k liiriQri Pofzil2 c ỊC ù c Rortiiivi 2 rankaj vU nar ratel Sa riia ratel S K. ixit and . Rathore 1 Division of Medicine 2Division of Velermnry Public Health ICAR-Indian Velermary Research Institute Izatnagar UP-243122 India Corresponding author ABSTRACT Keywords Antioxidant therapy Gastric mucosa Helicobacter pylori Oxidative stress Triple therapy Article Info Accepted 20 February 2018 Available Online 10 March 2018 The most common clinical condition reported in dogs is acid related diseases in the stomach like gastric disorders due to a structural and functional defect in gastric mucosa. The most important factor for the development of gastritis peptic ulcer disease and gastric cancer in human is Helicobacter pylori. In the cases of gastric disorder lesions in canine gastric mucosa is closely similar to their human counterparts. Many etiological factors are responsible for oxidative stress due to excessive generation of reactive oxygen species as a cause of gastric mucosal damage. The bacteria exist lifelong in the stomach of the untreated patient. This article reviews the classification some possible etiopathogenesis diagnosis and possible differential diagnosis and major strategies of therapy against acid disorders Fluid therapy proton pump inhibitors H-2 blocker cytoprotective with an update on the management of oxidative stress with antioxidant therapy Ascorbic acid N-acetyl cysteine Vitamin E and Triple therapy for management of Helicobacter pylori induced gastric disorders. Introduction Gastric diseases of dogs are usually gastric mucosal inflammation ulceration obstruction or neoplasia. Gastritis is the

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