TAILIEUCHUNG - New approach in minimally invasive surgery for treatment of rectal cancer: Transanal laparoscopic surgery

Objectives: To assess results of transanal total mesorectal excision laparoscopic surgery for treatment of the middle and low rectal cancer. Subjects and method: Clinical intervention, prospective, follow-up study without comparison in 45 patients with middle and low rectal cancer underwent transanal total mesorectal excision in Gastrointestinal Surgery Department, 108 Millitary Central Hospital, from July 2017 to August 2018. | Journal of military pharmaco-medicine no1-2019 NEW APPROACH IN MINIMALLY INVASIVE SURGERY FOR TREATMENT OF RECTAL CANCER: TRANSANAL LAPAROSCOPIC SURGERY Ngo Tien Khuong1; Nguyen Anh Tuan2; Nguyen To Hoai2 Nguyen Van Du2; Pham Van Hiep2 SUMMARY Objectives: To assess results of transanal total mesorectal excision laparoscopic surgery for treatment of the middle and low rectal cancer. Subjects and method: Clinical intervention, prospective, follow-up study without comparison in 45 patients with middle and low rectal cancer underwent transanal total mesorectal excision in Gastrointestinal Surgery Department, 108 Millitary Central Hospital, from July 2017 to August 2018. Results: The mean operative time was ± minutes. Operative morbidity rate was , no operative mortality. The macroscopic quality assessment of the resected specimen was complete in , nearly complete in . The mean number of harvested lymph nodes was ± ; the mean follow-up time was ± months, one patient () developed local and distant recurrence, disease-free survival and overall survival rates was and 100%, respectively. Conclusion: The transanal total mesorectal excision technique is feasible and safe, the good early outcomes, the high-quality of total mesorectal excision specimens for treatment in middle and low rectal cancer. * Keywords: Rectal cancer; Transanal total mesorectal excision; Laparoscopic operation. INTRODUCTION lymphatic drainage, to optimize locoregional clearance. The oncologic outcome is the most important goal in surgery for treatment of rectal cancer, followed by the preservation of sphincter and patients without artificial anus. To achieve both goals are still big challenges for colorectal surgeons. The up to down approach of TME has not been satisfactory for oncologic outcomes in low rectal cancer [2]. Several technical challenges are associated with laparoscopic treatment of distal rectal tumors in patients with narrow pelvis

• Y khoa - Dược
• Rectal cancer
• Transanal total mesorectal excision
• Laparoscopic operation
• Computed tomography
• Transanal endoscopic microsurgery
• Laparoscopic assistance
• BMC Cancer
• Paired rectal cancer cell lines
• Gene expression
• Total mesorectal excision
• Microarray analysis
• Primary rectal cancer
• Beyond total mesorectal excision plane
• Locally recurrent rectal cancer
• Benchmarking study
• Operative decision making
• Endoscopic ultrasound
• Rectal cancer stage
• Rectal tumors quickly
• Hypoechoic property
• Neoadjuvant chemotherapy
• Colorectal cancer
• Preoperative chemoradiotherapy
• Locally advanced rectal cancer
• Mutation load
• Receive radiotherapy
• Low rectal cancer
• High rectal cancer
• Laparoscopic surgery
• Oncological outcomes
• Propensity score matching
• Fluorouracil based preoperative chemoradiotherapy
• Locoregionally advanced rectal cancer
• Neoadjuvant chemoradiotherapy
• Machine learning
• Early cost effectiveness analysis
• Navigation technology
• Early health technology assessment
• Local recurrent rectal cancer
• Preliminary results
• Robotic approach in rectal cancer surgery
• Rectal cancer surgery
• Underwent robotic surgery
• Ultra low anterior resection
• Non operative management
• Chemoradiation therapy
• Clinical complete response
• Pathologic complete response
• Adjuvant chemotherapy
• Phase III randomized trials
• Transanal surgery
• Distal rectal cancer
• Disease free survival rates
• Double team
• Mid low rectal cancer
• Transanal total mesorectal excision in treatment
• Double team or single team
• Rectal neoplasms
• Distant metastasis
• Capecitabine remains controversial
• Prognostic factor
• Intraperitoneal free cancer cells
• Cancer cells harvested
• Protein array
• Serum proteins
• Contemporary cancer therapy emphasize
• Biological indicators
• Radiation recall
• Neoadjuvant radiation therapy
• Metastatic disease
• Acute toxicity
• Intensified neoadjuvant radiochemotherapy
• Cancer related survival
• Disease free survival
• T cell infiltration
• Immune checkpoint blockade
• Cancer treatment
• Tumour stroma ratio
• Biological molecules
• Concurrent chemoradiotherapy
• Chloride channels in glioblastoma
• CCRT response
• Cancer cell motility
• Semi quantitatively assess
• Various clinicopathological features
• Abscopal effect
• Anti tumor effects
• Radiation therapy
• Immune checkpoint molecule