TAILIEUCHUNG - Ebook Medicinal plants in asia for metabolic syndrome - Natural products and molecular basis: Part 2

Part 2 book “Medicinal plants in asia for metabolic syndrome - Natural products and molecular basis” has contents: Inhibiting insulin resistance and accumulation of triglycerides and cholesterol in the liver, increasing the sensitivity of adipocytes and skeletal muscle cells to insulin, inhibiting low-density lipoproteins intimal deposition and preserving nitric oxide function in the vascular system. | 3 Inhibiting Insulin Resistance and Accumulation of Triglycerides and Cholesterol in the Liver Visceral obesity favors the generation of reactive oxygen species, plasmatic nonesterified fatty acids, tumor necrosis factor-α, and interleukin-6 that act synergistically to bring about hepatic insulin Insulin resistance evokes a subnormal hepatic storage of glucose into glycogen and increases glucose production by the liver from glycogen, as well as de novo synthesis of glucose (gluconeogenesis) accounting for a fasting glycaemia, above mmol/L (110 mg/dL) and below mmol/L (125 mg/dL).2 In a state of insulin resistance, insulin is unable to suppress lipolysis in adipocytes and to activate adipose tissues endothelial lipoprotein lipase resulting in increased plasma nonesterified fatty acid supply to the liver that translates into increased hepatic production of very low-density lipoprotein levels and atherogenic –5 According to the National Cholesterol Education Program Adult Treatment Panel (ATP) III definition, metabolic syndrome will be present if at least three of the following criteria are met: waist circumference more than 40 inches (men) or 35 inches (women), blood pressure more than 130/85 mmHg, fasting triglyceride level superior to 150 mg/dl, fasting high-density lipoprotein–cholesterol below 40 mg/dL (men) or 50 mg/dL (women), and fasting blood sugar above 100 mg/ Excess of plasma glucose and triglycerides in metabolic syndrome result is fatty acid accumulation in the liver disrupting hepatocytes function leading to nonalcoholic Thus, inhibiting insulin resistance and accumulation of triglycerides and cholesterol in the liver with natural products constitute one therapeutic strategy to prevent or manage insulin resistance in metabolic syndrome. Myristica fragrans Hout. Synonyms: Myristica aromatica Lam.; Myristica moschata Thunb.; Myristica officinalis . Common names: buah pala (Malay); ru du

TỪ KHÓA LIÊN QUAN
TAILIEUCHUNG - Chia sẻ tài liệu không giới hạn
Địa chỉ : 444 Hoang Hoa Tham, Hanoi, Viet Nam
Website : tailieuchung.com
Email : tailieuchung20@gmail.com
Tailieuchung.com là thư viện tài liệu trực tuyến, nơi chia sẽ trao đổi hàng triệu tài liệu như luận văn đồ án, sách, giáo trình, đề thi.
Chúng tôi không chịu trách nhiệm liên quan đến các vấn đề bản quyền nội dung tài liệu được thành viên tự nguyện đăng tải lên, nếu phát hiện thấy tài liệu xấu hoặc tài liệu có bản quyền xin hãy email cho chúng tôi.
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.