TAILIEUCHUNG - Ebook Self assessment & review gynecology (9/E): Part 2

Part 2 book “Self assessment & review gynecology” has contents: Uterine fibroid, endometriosis and dysmenorrhea, disorders of menstruation, gynecological diagnosis and operative surger, gynecological oncology, miscellaneous question bank. | Chapter 11 Leiomyomata/Fibroids: Benign smooth muscle tumor of the uterus Fibroid is an estrogen- Uterine Fibroid FIBROIDS ¾¾ Fibroids are the most common benign solid tumors in ¾¾ It is the most common pelvic ¾¾ Most common age group affected is 35–45 yearsQ ¾¾ Fibroids are most commonly seen in nulliparous ¾¾Locations of fibroid is described as follows (Fig. ): dependent tumor Etiology/Pathogenesis of Fibroids Fig. :  Locations of fibroid Diseases commonly associated with leiomyomas— • Follicular cysts of ovary • Endometrial hyperplasia • Endometrial cancer • Endometriosis Fibroids are more common in— • Nulliparous females • Infertile females • Black women Fibroid is monoclonal in origin. Multiple chromosomal abnormalities are detected in 50% of all fibroids—most common being translocation between the long arms of chromosomes 12 and 14 followed by deletion of long arm of chromosome Y. Fibroids are related to both estrogen and progesterone. Risk of fibroid increases as obesity increases Smoking is protective for fibroids Increasing parity decreases its incidence Most Common in Fibroid • Most common (M/c) variety of fibroid • • • • • • • • • • • • • • Fibroid with maximal symptoms To start with, all fibroids are M/c fibroid to undergo malignant change M/c fibroid to cause retention of urine Torsion is most common in Fibroid causing pseudo Meigs syndrome M/c menstrual symptom of fibroid Inversion is seen in M/c symptom of fundal fibroid Fibroid which leads to maximum abortion Wandering or parasitic fibroid Lantern on dome of St Paul Pseudocervical fibroid M/c fibroid to undergo calcareous degeneration – Intramural/interstitial (75%) followed by submucous (15%) and subserous (10%) – Submucous fibroid – Interstitial (Intramural) – Submucous – Posterior cervical – Large pedunculated subserous fibroid – Subserous fibroid – Menorrhagia – Fundal fibroid – Menorrhagia – Submucous .

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