TAILIEUCHUNG - Longevity in some wild type and hybrid strains of Drosophila melanogaster

It is known that aging is a multifactorial mechanism composed of both genetic and environmental components. The main evolutionary theories of aging are antagonistic pleiotropy and mutation accumulation, neither of which has substantial experimental support yet. In this study, the longevities of three wild type strains of Drosophila melanogaster and F1 hybrids derived from them were determined. | Turk J Biol 24 (2000) 321–329 © TÜBİTAK Longevity in Some Wild Type and Hybrid Strains of Drosophila melanogaster Şükran ÇAKIR Ankara University, Faculty of Veterinary, Department of Genetics, 06110 Ankara-TURKEY Ali Nihat BOZCUK Hacettepe University, Department of Biology, Beytepe Campus, Ankara-TURKEY Received: Abstract: It is known that aging is a multifactorial mechanism composed of both genetic and environmental components. The main evolutionary theories of aging are antagonistic pleiotropy and mutation accumulation, neither of which has substantial experimental support yet. In this study, the longevities of three wild type strains of Drosophila melanogaster and F1 hybrids derived from them were determined. Heterosis caused an increase in the adult lifespan of F1 hybrids. Key Words: Drosophila melanogaster, longevity, aging, and heterosis. Drosophila melanogaster’in Bazı Doğal Tip ve Melez Soylarında Ömür Uzunluğu Özet: Yaşlanmanın genetik ve çevresel bileşenlerden oluşan çok faktörlü bir mekanizma olduğu bilinir. Yaşlanmanın temel evrimsel teorilerinden antagonistic pleiotropy ve mutation accumulation’den hiçbiri henüz yeterli deneysel desteğe sahip değildir. Bu çalışmada Drosophila melanogaster’in üç doğal soyu ve bunlardan elde edilen F1 melezlerinde ömür uzunluğu belirlendi. F1 ergin melezlerinde melez dinçliği ömür uzunluğunda artışa neden oldu. Anahtar Sözcükler: Drosophila melanogaster, ömür uzunluğu, yaşlanma ve melez dinçliği. Introduction In all organisms, the process of aging is characterized by a gradual loss of homeostatic maintenance functions and physiological fitness. Species of the genus Drosophila, commonly known as fruit flies, are good model systems for research in aging. Drosophila are extremely well-known genetically, developmentally, and otherwise. They are also genetically analogous to mammalian species in most respects. Their life span is remarkably variable and in several respects a typical quantitative character in .

• Sinh học
• Drosophila melanogaster
• Hybrid strains
• Multifactorial mechanism
• Antagonistic pleiotropy
• Mutation accumulation
• F1 hybrids
• Biểu hiện vượt mức Drosophila ubiquitin carboxyl terminal hydrolase
• Phát triển mắt ruồi giấm Drosophila melanogaster
• Phát triển mắt ruồi giấm
• Mô hình ruồi giấm Drosophila melanogaster
• BMC Genomics
• RNA sequencing
• Non coding genes
• Drosophila genes
• Genome Biology
• Intron retention
• Systems genetics
• Small exon
• Drosophila melanogaster strains
• Scientific reports
• scientific research
• biochemistry
• biochemical studies
• medical knowledge
• Egg and larvae development
• Organic phosphoric insecticide
• Diazinon’s toxicity
• Chinook salmon
• Fruit fly
• S Transferase enzymes
• Analysis of variance
• Esterase 6 enzyme activity
• Drosophila melanogaster mutants
• Minority advantage
• Artificial scent
• Wing clipping
• Maintaining genetic
• Electromagnetic fields
• Pulsed radiofrequency
• Electromagnetic spectrum
• Ecdysteroid hormones
• Alcohol dehydrogenase
• Adh null mutations
• Partial dominance
• ADH polymorphism
• Somatic mutation and recombination test
• Somatic mutation
• Wing spot test
• Para hydroxybenzoic acid
• Functional coexpression
• Genome instability
• S2 cultured cells
• Segmental aneuploidy
• RNA interference
• Ruồi giấm
• Nuôi ruồi giấm
• Nuôi chim yến
• Thức ăn chăn nuôi
• Chăn nuôi ruồi giấm
• Thức ăn bổ sung cho chim yến
• Điều trị bệnh Parkinson
• Điều trị bệnh Parkinson của resveratrol
• Bệnh thoái hóa thần kinh
• Tế bào thần kinh sinh dopamine
• Immune response
• Time course RNA seq
• Granger causality
• Circadian clock
• Diurnal preference
• Being diurnal
• Individuals exists
• Ancient sequences
• Gene finding
• Protein coding genes
• Bioinformatics algorithms
• Transcription initiation
• High resolution transcription start site
• Enhancer RNAs”
• Journal of Zoology
• Survival rate
• Development time
• Antioxidant enzymes
• BMC Genetics
• Amyloid β peptides
• Antimicrobial peptides
• Transcription factor FOXO
• Peroxiredoxin 5
• Gamma carboxylase
• Intron splicing
• Small intron
• Drosophila gamma carboxylase
• Electrochemical gradient
• Follicle cell
• Pattern formation
• Drosophila ovarian follicles
• Video tracking
• Automatic phenotyping
• Drosophila larvae
• Neuromuscular junctions
• Circular RNAs
• Drosophila photoreceptors
• Age associated visual decline
• Cool temperature acclimation
• Transcriptional control
• Drosophila cells