TAILIEUCHUNG - Histology of adipose tissue inflammation in Dercum’s disease, obesity and normal weight controls: a case control study

Background: Dercum’s disease (DD) is characterised by obesity and chronic pain ( 3 months) in the adipose tissue. The pathogenesis of DD is unknown, but inflammatory components have been proposed. In previous reports and studies, an inconsistent picture of the histological appearance of the adipose tissue in DD has been described. The aim of this investigation was to examine the histological appearance of adipose tissue in patients with DD, with particular focus on inflammatory signs. Methods: Fat biopsies were sampled from painful regions from 53 patients with DD. In 28 of the patients, a control adipose tissue biopsy was taken. | Hansson et al. Journal of Inflammation 2011 8 24 http content 8 1 24 JOURNAL OF INFLAMMATION RESEARCH Open Access Histology of adipose tissue inflammation in Dercum s disease obesity and normal weight controls a case control study Emma Hansson1 Henry Svensson1 Unne Stenram2 and Hakan Brorson1 Abstract Background Dercum s disease DD is characterised by obesity and chronic pain 3 months in the adipose tissue. The pathogenesis of DD is unknown but inflammatory components have been proposed. In previous reports and studies an inconsistent picture of the histological appearance of the adipose tissue in DD has been described. The aim of this investigation was to examine the histological appearance of adipose tissue in patients with DD with particular focus on inflammatory signs. Methods Fat biopsies were sampled from painful regions from 53 patients with DD. In 28 of the patients a control adipose tissue biopsy was taken from a location where the patient did not experience any pain. In addition fat biopsies were sampled from 41 healthy pain-free obese control patients and 11 healthy pain-free normal weight control patients. The extent of inflammation was evaluated on histological sections stained with haematoxylin-eosin. Results There was no statistically significant difference in the extent of inflammation between the biopsies from the painful knee and the biopsies from the non-painful area p nor between the biopsies from the abdomen and the biopsies from the non-painful area p in patients with DD. A statistically significant difference in extent of inflammation was observed between DD and obese control patients regarding the abdomen p but not the knee p . There were no differences in extent of inflammation between DD patients and normal weight controls p . Conclusion The findings suggest that there is an inflammatory response in the adipose tissue in DD. However this response is not more pronounced than that in .

• Báo cáo khoa học
• inflammatory fat
• obese
• obesity control
• weight control
• overweight related diseases
• diet
• báo cáo khoa học
• báo cáo y học
• công trình nghiên cứu về y học
• tài liệu về y học
• cách trình bày báo cáo
• Non alcoholic fatty liver disease
• Phosphodiesterase 3B
• Oxidative stress
• Hepatic steatosis
• Insulin resistance
• Pro inflammatory cytokines
• BMC Pediatrics
• Body mass index
• Body fat distribution
• Paediatrics Clinic
• Waist to hip ratio
• Dual energy X ray absorptiometry
• BMC Veterinary Research
• Tea polyphenols
• COX 2 expression
• Inflammatory cytokines
• Inducible nitric oxide synthase
• Fitness Plan
• metabolic makeup
• training methods
• diet plan
• 30 Day Diet
• Kỹ thuật diệt may
• kinh nghiệm diệt may
• cẩm nang diệt may
• hướng dẫn diệt may
• tài liệu diệt may
• bài giảng diệt may
• Detox Box
• Abs Diet
• Weight Loss
• Writing Diet
• Sonoma Diet
• Phần mềm diệt virus
• Phần mềm diệt virus miễn phí
• Phần mềm diệt virus tốt nhất
• Phần mềm diệt virus 2014
• Phần mềm diệt virus tốt nhất 2014
• Tính năng phần mềm diệt virus
• diet appropriate
• diet breaks
• Crash Dieting
• moderate diet
• nonessential nutrients
• RAW FOOD
• DETOX DIET
• FOOD DETOX
• DIET RECIPES
• Limited Budget
• RAW FOODIST
• GDA DIET
• KCAL PLANS
• MEAL PLANNERS
• DIET CYCLE
• GDA LEAP
• GDA LABELS
• Kỹ thuật diệt chuột
• Phương pháp diệt chuột
• Thuốc thiệt chuột
• Cấp cứu ngộ độc thuốc diệt chuột
• Diệt chuột bằng hóa chất
• Diệt chuột bằng nhân công
• côn trùng gây hại
• kỹ thuật diệt côn trùng
• kinh nghiệm diệt côn trùng
• phương pháp diệt côn trùng
• hướng dẫn diệt côn trùng
• biện pháp diệt côn trùng
• Cách diệt côn trùng
• Cách diệt gián
• Cách đuổi muỗi
• Cách diệt bướm
• Cách diệt kiến
• Cách diệt bọ chét
• Cách diệt mối tận gốc ngay tại nhà
• Cách diệt mối
• Diệt mối tận gốc
• Biện pháp diệt mối
• Diệt mối tận gốc tại nhà
• Cách diệt virus đã nhiễm vào máy vi tính
• Cách diệt virus
• Phương pháp diệt virus
• Bảo vệ máy tính
• Kỹ năng diệt virus máy tính
• Body weight
• Feed efficiency
• Energy diet
• Protein diet
• Economics of cross bred
• Guar korma
• Groundnut cake
• Diet of buffalo calves
• A good alternate
• Replace groundnut cake
• Higher NH3 N
• BMC Cancer
• High fat diet
• Low fat diet
• Hepatocellular carcinoma
• Non alcoholic steatohepatitis
• Patients with type 2 diabetes
• Knowledge on the diet
• Practice on diet
• Outpatients with type 2 diabetes
• General information