TAILIEUCHUNG - Báo cáo sinh học: "Consistency of the Neighbor-Net Algorithm"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí y học Molecular Biology cung cấp cho các bạn kiến thức về ngành sinh học đề tài: Consistency of the Neighbor-Net Algorithm. | Algorithms for Molecular Biology BioMed Central Research Consistency of the Neighbor-Net Algorithm David Bryant1 Vincent Moulton 2 and Andreas Spillner2 Open Access Address Department of Mathematics University of Auckland Private Bag 92019 Auckland NZ and 2School of Computing Sciences University of East Anglia Norwich NR4 7TJ UK Email David Bryant - bryant@ Vincent Moulton - Andreas Spillner - aspillner@ Corresponding author Published 28 June 2007 Received 26 March 2007 Algorithms for Molecular Biology 2007 2 8 doi 1748-7188-2-8 Accepted 28 June 2007 This article is available from http content 2 1 8 2007 Bryant et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Neighbor-Net is a novel method for phylogenetic analysis that is currently being widely used in areas such as virology bacteriology and plant evolution. Given an input distance matrix Neighbor-Net produces a phylogenetic network a generalization of an evolutionary or phylogenetic tree which allows the graphical representation of conflicting phylogenetic signals. Results In general any network construction method should not depict more conflict than is found in the data and when the data is fitted well by a tree the method should return a network that is close to this tree. In this paper we provide a formal proof that Neighbor-Net satisfies both of these requirements so that in particular Neighbor-Net is statistically consistent on circular distances. 1 Background Phylogenetics is concerned with the construction and analysis of evolutionary or phylogenetic trees and networks to understand the evolution of species populations and individuals 1 . Neighbor-Net is a

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