TAILIEUCHUNG - báo cáo khoa học: "Chylous effusion presenting in a 37-year-old woman with severe hypothyroidism: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Chylous effusion presenting in a 37-year-old woman with severe hypothyroidism: a case report | Koo et al. Journal of Medical Case Reports 2010 4 336 http content 4 1 336 jAc JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Chylous effusion presenting in a 37-year-old woman with severe hypothyroidism a case report Kevin SH Koo1 Rand Barnard2 Frank T Kagawa3 Weichia Chen4 Irma Hinojosa Abstract Introduction We report what is to the best of our knowledge the second adult case of chylothorax clearly associated with severe hypothyroidism in the English-language medical literature. To the best of our knowledge this is the first case of its kind reported without a prior history of malignancy. Case presentation A 37-year-old Hispanic woman with no reported significant past medical history initially presented with shortness of breath and inability to lose weight. She was found to have a large chylous effusion requiring chest-tube drainage as well as severe hypothyroidism. After several weeks of thyroid hormone-replacement therapy the formation of chylous pleural fluid in the patient greatly diminished and the chest tube was removed. Upon long-term follow-up her minimal residual effusion remains stable on serial chest radiographs. Conclusion Although the exact pathophysiologic relation between low thyroid hormone levels and chyle formation remains to be elucidated hypothyroidism should be a diagnostic consideration in patients with chylous effusions especially those refractory to conventional treatments. Introduction Hypothyroidism is a relatively common disorder among the general population and its incidence only increases with age. Typically patients present with a subclinical picture but left untreated the condition can develop into overt hypothyroidism. The prevalence of overt hypothyroidism has been estimated to be whereas subclinical hypothyroidism can be as high as 1 . One previous case report described a chylothorax clearly associated with hypothyroidism 2 however the patient described in that case report had a .

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