TAILIEUCHUNG - Báo cáo khoa học: "Volumetric modulated arc therapy is superior to conventional intensity modulated radiotherapy a comparison among prostate cancer patients treated in an Australian centre"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Volumetric modulated arc therapy is superior to conventional intensity modulated radiotherapy a comparison among prostate cancer patients treated in an Australian centre. | Fogarty et al. Radiation Oncology 2011 6 108 http content 6 1 108 RADIATION ONCOLOGY RESEARCH Open Access Volumetric modulated arc therapy is superior to conventional intensity modulated radiotherapy -a comparison among prostate cancer patients treated in an Australian centre Gerald B Fogarty1 Diana Ng1 Guilin Liu1 Lauren E Haydu2 3 and Nastik Bhandari1 Abstract Background Radiotherapy technology is expanding rapidly. Volumetric Modulated Arc Therapy VMAT technologies such as RapidArc RA may be a more efficient way of delivering intensity-modulated radiotherapylike IM treatments. This study is an audit of the RA experience in an Australian department with a planning and economic comparison to IM. Methods 30 consecutive prostate cancer patients treated radically with RA were analyzed. Eight RA patients treated definitively were then completely re-planned with 3D conformal radiotherapy 3D and a conventional sliding window IM technique and a new RA plan. The acceptable plans and their treatment times were compared and analyzed for any significant difference. Differences in staff costs of treatment were computed and analyzed. Results Thirty patients had been treated to date with eight being treated definitely to at least 74 Gy nine post high dose brachytherapy HDR to and 13 post prostatectomy to at least 64Gy. All radiotherapy courses were completed with no breaks. Acute rectal toxicity by the RTOG criteria was acceptable with 22 having no toxicity seven with grade 1 and one had grade 2. Of the eight re-planned patients none of the 3D three-dimensional conformal radiotherapy plans were acceptable based on local guidelines for dose to organs at risk. There was no statistically significant difference in planning times between IM and RA p . IM had significantly greater MUs per fraction vs p total beam time per course vs hours p and average treatment staff cost per patient radiotherapy course vs .

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