TAILIEUCHUNG - báo cáo khoa học: " Recruitment activities for a nationwide, population-based, group-randomized trial: the VA MI-Plus study"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Recruitment activities for a nationwide, population-based, group-randomized trial: the VA MI-Plus study | Funkhouser et al. Implementation Science 2011 6 105 http content 6 1 105 Implementation Science IMPLEMENTATION SCIENCE RESEARCH Open Access Recruitment activities for a nationwide population-based group-randomized trial the VA Ml-Plus study Ellen Funkhouser1 2 Deborah A Levine2 3 4 Joe K Gerald5 Thomas K Houston6 Nancy K Johnson 1 Jeroan J Allison6 and Catarina I Kiefe6 Abstract Background The Veterans Health Administration VHA oversees the largest integrated healthcare system in the United States. The feasibility of a large-scale nationwide group-randomized implementation trial of VHA outpatient practices has not been reported. We describe the recruitment and enrollment of such a trial testing a clinician-directed Internet-delivered intervention for improving the care of postmyocardial infarction patients with multiple comorbidities. Methods With a recruitment goal of 200 eligible community-based outpatient clinics parent VHA facilities medical centers were recruited because they oversee their affiliated clinics and the research conducted there. Eligible facilities had at least four VHA-owned and -operated primary care clinics an affiliated Institutional Review Board IRB and no ongoing potentially overlapping quality-improvement study. Between December 2003 and December 2005 in two consecutive phases we used initial and then intensified recruitment strategies. Results Overall 48 of 66 73 eligible facilities were recruited. Of the 219 clinics and 957 clinicians associated with the 48 facilities 168 78 clinics and 401 42 clinicians participated. The median time from initial facility contact to clinic enrollment was 222 days which decreased by over one-third from the first to the second recruitment phase medians 323 and 195 days respectively p .001 when more structured recruitment with physician recruiters was implemented and a dedicated IRB manager was added to the coordinating center staff. Conclusions Large group-randomized trials .

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