TAILIEUCHUNG - báo cáo khoa học: "Expectation of variance due to mitochondrial genes from several mating designs"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Expectation of variance due to mitochondrial genes from several mating designs | Génét. Sél. Evol. 1987 19 2 171-180 Expectation of variance due to mitochondrial genes from several mating designs . ROTHSCHILD and L. OLLIVIER Department of Animal Science Iowa State University Ames Iowa 50011 . . Station de Génétique quantitative et appliquée Centre de Recherches de Jouy-en-Josas F 78350 Jouy-en-iosas. Summary Genetic variation due to non-nuclear DNA has been generally ignored by animal breeders. Recent evidence has confirmed that mitochondrial inheritance is predominantly of maternal origin in mammals. Advances in biotechnology make manipulation of non-nuclear and nuclear material in embryos likely in the future. Estimation of the relative importance of direct maternal and mitochondrial genetic variation would help in assessing the value of these new technologies. Expectations of causal components of variance from previously used mating and crossfostering designs are modified to include variation due to mitochondrial cytoplasmic material. The efficiencies of the designs are compared as well as the statistical consequences of adding the mitochondrial component to the original models. The designs presented have limitations due to possible confounding of maternal grand-maternal and mitochondrial effects and to their being not adequate for all animal species and traits. However techniques such as embryo transfer can circumvent those difficulties. Possibilities of using improved designs clearly depend on biotechnological advances and on the cost of implementing those new techniques. Key words Mitochondrial inheritance direct and maternal genetic variances covariances. Résumé Esperance de la variance due à des genes mitochondriaux dans divers plans d accouplement La variation génétique due à 1 ADN extra-nucléaire a généralement été ignorée en génétique animale. Des résùítats récents confirment que rhérédité mitochondriale est d une manière prédo-minante d origine maternelle chez les mammiferes. Les progrès de la biotechnologie .

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