TAILIEUCHUNG - Báo cáo khoa hoc:" Genetic diversity of eleven European pig breeds"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Genetic diversity of eleven European pig breeds | Genet. Sel. Evol. 32 2000 187-203 187 INRA EDP Sciences Original article Genetic diversity of eleven European pig breeds Guillaume LAVALa Nathalie lANNUCCELLIa Christian LEGAULTb Denis MILANa Martien Elisabetta GIUFFRAd Leif ANDERSSONd Peter H. NISSENe Claus B. J0RGENSENe Petra BEECKMANNf Hermann GELDERMANNf Jean-Louis FOULLEYb Claude CHEVALETa Louis OLLIVIERb a Laboratoire de génétique cellulaire Institut national de la recherche agronomique BP 27 31326 Castanet-Tolosan Cedex France b Station de génétique quantitative et appliquée Institut national de la recherche agronomique 78352 Jouy-en-Josas Cedex France c Wageningen Institute of Animal Science Wageningen Agricultural University Wageningen The Netherlands d Department of Animal Breeding and Genetics Swedish University of Agricultural Sciences Uppsala Sweden e Division of Animal Genetics the Royal Veterinary and Agricultural University Copenhagen Denmark f Department of Animal Breeding and Biotechnology Universitat Hohenheim Stuttgart Germany Received 8 July 1999 accepted 14 January 2000 Abstract - A set of eleven pig breeds originating from six European countries and including a small sample of wild pigs was chosen for this study of genetic diversity. Diversity was evaluated on the basis of 18 microsatellite markers typed over a total of 483 DNA samples collected. Average breed heterozygosity varied from to . Genotypic frequencies generally agreed with Hardy-Weinberg expectations apart from the German Landrace and Schwabisch-Hallisches breeds which showed significantly reduced heterozygosity. Breed differentiation was significant as shown by the high among-breed fixation index overall Fst and confirmed by the clustering based on the genetic distances between individuals which grouped essentially all individuals in 11 clusters corresponding to the 11 breeds. The genetic distances between breeds were first used to construct phylogenetic trees. The trees indicated that a genetic drift .

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