TAILIEUCHUNG - Báo cáo sinh học: "Effects of major histocompatibility complex on antibody response in F 1 and F 2 crosses of chicken lines"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Effects of major histocompatibility complex on antibody response in F 1 and F 2 crosses of chicken lines | 283 Genet Sei Evol 1993 25 283-296 Elsevier INRA Original article Effects of major histocompatibility complex on antibody response in F and F2 crosses of chicken lines MH Pinard1 AJ Van der Zijpp2 1 Wageningen Agricultural University Departement of Animal Husbandry Wageningen 2 DLO-Research Institute for Animal Production Schoonoord Zeist The Netherlands Received 12 May 1992 accepted 5 January 1993 Summary - Lines of chickens selected for 9 generations for high H and low L antibody Ab response to sheep red blood cells SRBC were crossed to produce Fi n 761 and F2 n 1033 populations. All animals were typed for major histocompatibility complex MHC B-types. Effects of MHC genotypes and haplotypes on the Ab titer to SRBC were estimated. The MHC genotypes and remaining genotype explained and 31 of the total variation of the Ab titer in the F2 respectively. Estimates of MHC effects in the F2 were similar to estimates in the selected lines. The 119 and 121 B-haplotypes were associated with a significantly higher response than the 114 and 124 B-haplotypes. These results confirm the hypothesis that changes in B-type distribution observed in the selected lines could be related to a direct or closely linked effect of MHC on the immune response. chicken humoral response selection cross major histocompatibility complex Resume - Effets du complexe majeur d histocompatibilite sur la réponse en anticorps dans des croisements Fl et F2 de lignées de poules. Des lignées de poules sélectionnées pendant 9 generations sur la réponse humorale haute et basse à des globules rouges de mouton ont été croisées afin de produire une Fl h 761 et une F h 1033 . Tons les animaux ont été analyses pour leurs types B du complexe majeur d histocompatibilite CMH . Les effets des genotypes et des haplotypes du CMH sur la réponse en anticorps aux globules rouges de mouton ont été estimés. Le genotype du CMH explique 2 5 de la variation totale de la réponse en anticorps dans la Fị alors que 1 .

• Báo cáo khoa học
• Báo cáo sinh học hay
• cách trình bày báo cáo
• báo cáo sinh học
• công trình nghiên cứu sinh học
• tài liệu về sinh học