TAILIEUCHUNG - Trends in Nonalcoholic Fatty Liver Disease–related Hospitalizations in US Children, Adolescents, and Young Adults

in addition to investing in new maternal and neonatal health tools and technologies, we aim to adapt interventions used in referral-level facilities so they can be used in homes, communities, and first-level clinics. Misoprostol’s availability in a pill form that does not require injection or refrigeration makes it particularly promising for use by midwives and other frontline workers in home, community, and first-level clinic settings. oxytocin in Uniject™ is another treatment tool being investigated for postpartum hemorrhage. this single-use, prefilled injection device with a temperature/ time indicator could help overcome some of the barriers associated with the conventional use of oxytocin. | Journal of Pediatric Gastroenterology and Nutrition 48 597-603 2009 by European Society for Pediatric Gastroenterology Hepatology and Nutrition and North American Society for Pediatric Gastroenterology Hepatology and Nutrition Trends in Nonalcoholic Fatty Liver Disease-related Hospitalizations in US Children Adolescents and Young Adults Corinna Koebnick Darios Getahun Kristi Reynolds Karen J. Coleman yAmy H. Porter Jean M. Lawrence ÍMark Punyanitya Virginia P. Quinn and Steven J. Jacobsen Department of Research and Evaluation Kaiser Permanente Southern California Pasadena CA Baldwin Park Medical Center Southern California Permanente Medical Group Baldwin Park CA and St. Luke s-Roosevelt Hospital Columbia University NY NY ABSTRACT Objective To investigate temporal trends of nonalcoholic fatty liver disease NAFLD and obesity among hospitalized US children adolescents and young adults over the past 2 decades and to examine potential sex disparities in NAFLD hospitalizations. Methods Hospitalization discharges with NAFLD or obesity were identified among children and young adults 6-25 years weighted n 91 687 413 from the 1986 to 2006 National Hospital Discharge Survey data. Age- and sex-specific rates and trends in hospitalizations with NAFLD and obesity were estimated. Rates were standardized to age distribution of the 2000 US Census population. Sex disparities were examined for the most recent period 2004 to 2006 weighted n 12 969 532 . Results Between 1986 to 1988 and 2004 to 2006 hospitalizations with NAFLD diagnosis increased from to 100 000 population P . During the same time hospitalizations with a diagnosis of obesity increased from to 100 000 population P . During 2004 to 2006 hospitalization rates with a diagnosis of NAFLD were higher among females than among males vs 100 000 population P as were hospitalizations with a diagnosis of obesity vs 100 000 population P . Obesity and diabetes were .

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