TAILIEUCHUNG - Báo cáo sinh học: " Genetic vaccine for tuberculosis (pVAXhsp65) primes neonate mice for a strong immune response at the adult stage"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Genetic vaccine for tuberculosis (pVAXhsp65) primes neonate mice for a strong immune response at the adult stage | Genetic Vaccines and Therapy BioMed Central Research Genetic vaccine for tuberculosis pVAXhsp65 primes neonate mice for a strong immune response at the adult stage Ana Cláudia Pelizon1 Douglas R Martins1 Sofia FG Zorzella1 Ana Paula F Trombone3 Júlio CC Lorenzi3 Robson F Carvalho2 Izaira T Brandão3 Arlete AM Coelho-Castelo3 Célio L Silva3 and Alexandrina Sartori 1 Address Department of Microbiology and Immunology Biosciences Institute São Paulo State University UNESP Botucatu São Paulo 18618000 Brazil department of Morphology Biosciences Institute São Paulo State University UNESP Botucatu São Paulo 18618-000 Brazil and department of Biochemistry and Immunology University of São Paulo USP Ribeirão Preto São Paulo 14049-900 Brazil Email Ana Cláudia Pelizon - acpelizon@ Douglas R Martins - douglasgta@ Sofia FG Zorzella - szorzella@ Ana Paula F Trombone - apfavaro@ Júlio CC Lorenzi - julioclorenzi@ Robson F Carvalho - rfcarvalho@ Izaira T Brandão - izausp@ Arlete AM Coelho-Castelo - arlete@ Célio L Silva - clsilva@ Alexandrina Sartori - sartori@ Corresponding author Open Access Published 29 November 2007 Received 23 July 2007 .J IA I I oz 1 a 70 ACCZ r n Accepted 29 November 2007 Genetic Vaccines and Therapy 2007 5 12 doi 1479-0556-5-12 This article is available from http content 5 1 12 2007 Pelizon et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Vaccination of neonates is generally difficult due to the immaturity of the immune system and consequent higher susceptibility to tolerance induction. Genetic immunization has been .

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