TAILIEUCHUNG - Báo cáo sinh học: " Genetic parameters related to environmental variability of weight traits in a selection experiment for weight gain in mice; signs of correlated canalised response"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Genetic parameters related to environmental variability of weight traits in a selection experiment for weight gain in mice; signs of correlated canalised response | Genet. Sel. Evol. 40 2008 279-293 INRA EDP Sciences 2008 DOI gse 2008003 Available online at Original article Genetic parameters related to environmental variability of weight traits in a selection experiment for weight gain in mice signs of correlated canalised response Noelia IbANez-Escriche1 Almudena MORENO2 Blanca NIETO3 Pepa PIQUERAS3 Concepcion Salgado3 Juan Pablo GutiERREZ3 1 Genètica i Millora Animal IRTA 25198 Lleida Spain 2 Departamento de Mejora Genética Animal INIA 28040 Madrid Spain 3 Departamento de Producción Animal Universidad Complutense de Madrid Av. Puerta de Hierro s n 28040 Madrid Spain Received 19 March 2007 accepted 15 November 2007 Abstract - Data from an experimental mice population selected from 18 generations to increase weight gain were used to estimate the genetic parameters associated with environmental variability. The analysis involved three traits weight at 21 days weight at 42 days and weight gain between 21 and 42 days. A dataset of 5273 records for males was studied. Data were analysed using Bayesian procedures by comparing the Deviance Information Criterion DIC value of two different models one assuming homogeneous environmental variances and another assuming them as heterogeneous. The model assuming heterogeneity was better in all cases and also showed higher additive genetic variances and lower common environmental variances. The heterogeneity of residual variance was associated with systematic and additive genetic effects thus making reduction by selection possible. Genetic correlations between the additive genetic effects on mean and environmental variance of the traits analysed were always negative ranging from to . An increase in the heritability of the traits was found when considering the genetic determination of the environmental variability. A suggested correlated canalised response was found in terms of coefficient of variation but it could be insufficient to compensate for the .

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