TAILIEUCHUNG - báo cáo khoa học: " LysoPC acyltransferase/PC transacylase activities in plant plasma membrane and plasma membrane-associated endoplasmic reticulum"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: LysoPC acyltransferase/PC transacylase activities in plant plasma membrane and plasma membrane-associated endoplasmic reticulum | BioMed Central BMC Plant Biology Research article Open Access LysoPC acyltransferase PC transacylase activities in plant plasma membrane and plasma membrane-associated endoplasmic reticulum Karin E Larsson1 J Magnus Kjellberg1 2 Henrik Tjellstrom1 and Anna Stina Sandelius 1 Address department of Plant and Environmental Sciences Goteborg University . Box 461 SE-405 30 Goteborg Sweden and 2Lead Discovery Informatics Team Lead Generation Department AstraZeneca R D Molndal Sweden Email Karin E Larsson - J Magnus Kjellberg - Henrik Tjellstrom - Anna Stina Sandelius - Corresponding author Published 28 November 2007 Received 23 March 2007 DAAT-- AA-7 ũtn Ali 1 A A Accepted 28 November 2007 BMC Plant Biology 2007 7 64 doi 1471-2229-7-64 This article is available from http 1471-2229 7 64 2007 Larsson et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The phospholipids of the plant plasma membrane are synthesized in the endoplasmic reticulum ER . The majority of these lipids reach the plasma membrane independently of the secretory vesicular pathway. Phospholipid delivery to the mitochondria and chloroplasts of plant cells also bypasses the secretory pathway and here it has been proposed that lysophospholipids are transported at contact sites between specific regions of the ER and the respective organelle followed by lysophospholipid acylation in the target organelle. To test the hypothesis that a corresponding mechanism operates to transport phospholipids to the plasma membrane outside the secretory pathway we investigated whether lysolipid acylation .

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