TAILIEUCHUNG - LC-NMR and Other Hyphenated NMR Techniques

Since the subject of nuclear magnetic resonance (NMR) was awarded its first Nobel Prize in 1952 due to its successful detection by Bloch and Purcell in 1945, the technology and its applications have developed tremendously. The first two decades were focused on technical developments of instrumentation and methodologies to apply to the structure determination of compounds. During the late 1970s, several research groups developed modifications of NMR probes to convert them to an online mode for the analysis of sample mixtures | LC-NMR and Other Hyphenated NMR Techniques LC-NMR and Other Hyphenated NMR Techniques Overview and Applications Maria Victoria Silva Elipe Amgen Inc. WILEY A JOHN WILEY SONS INC. PUBLICATION Copyright 2012 by John Wiley Sons Inc. All rights reserved. Published by John Wiley Sons Inc. Hoboken New Jersey. Published simultaneously in Canada. No part of this publication may be reproduced stored in a retrieval system or transmitted in any form or by any means electronic mechanical photocopying recording scanning or otherwise except as permitted under Section 107 or 108 of the 1976 United States Copyright Act without either the prior written permission of the Publisher or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center Inc. 222 Rosewood Drive Danvers MA 01923 978 750-8400 fax 978 750-4470 or on the web at . Requests to the Publisher for permission should be addressed to the Permissions Department John Wiley Sons Inc. 111 River Street Hoboken NJ 07030 201 748-6011 fax 201 748-6008 or online at http go permission. Limit of Liability Disclaimer of Warranty While the publisher and author have used their best efforts in preparing this book they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials. The advice and strategies contained herein may not be suitable for your situation. You should consult with a professional where appropriate. Neither the publisher nor author shall be liable for any loss of profit or any other commercial damages including but not limited to special incidental consequential or other damages. For general information on our other products and services or for technical support please contact our Customer Care Department within

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