TAILIEUCHUNG - Biochemistry, 4th Edition P93

Biochemistry, 4th Edition P93. Continuing Garrett and Grisham's innovative conceptual and organizing framework, "Essential Questions," BIOCHEMISTRY guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. Streamlined for increased clarity and readability, this edition also includes new photos and illustrations that show the subject matter consistently throughout the text. New end-of-chapter problems, MCAT practice questions, and the unparalleled text/media integration with the power of CengageNOW round out this exceptional package, giving you the tools you need to both master course concepts and develop critical problem-solving skills you can draw upon. | How Is the Genetic Information Shuffled by Genetic Recombination 883 b Junction binding RuvA Branch migration Resolution RuvB RuvC CENGAGENOW ACTIVE FIGURE Model for the resolution of a Holliday junction in by the RuvA RuvB and RuvC proteins. a Ribbon diagram of the RuvA monomers have an overall L shape pdb id 1CUK . b Model for RuvA RuvB action left .The RuvA tetramer fits snugly within the Holliday junction point. center Oppositely facing RuvB hexameric rings assemble on the heteroduplexes with the DNA passing through their RuvB hexamers act as motors to promote branch migration by driving the passage of the DNA duplexes through themselves. right Binding of RuvC at the Holliday junction and strand scission by its nuclease locations of the RuvC active sites are indicated by the scissors. c Charge distribution on the concave surface of an RuvA tetramer. Blue indicates positive charge and red negative charge. Note the overall positive charge on this surface of RuvA 4 with the exception of the four red negatively charged pins at its center. d Structural model for the interaction of RuvA 4 with the hypothesized square-planar Holliday junction center pdb id 1C7Y . Adapted from Figures 1 2 and 3 in Rafferty J. B. et al. 1996. Crystal structure of DNA recombination protein RuvA and a model for its binding to the Holliday junction. Science 274 415-421. Test yourself on the concepts in this figure at login. c or single-strand uptake . Strand assimilation does not occur if there is no sequence homology between the ssDNA and the invaded DNA duplex. The DNA strand displaced by the invading 3 -terminal ssDNA is free to anneal with the 5 -terminal strand in the original DNA a step that is also mediated by RecA protein and SSB Figure . The result is a Hollidayjunction the classic intermediate in genetic recombination. RuvA RuvB and RuvC Proteins Resolve the Holliday Junction to Form the .

• Sinh học
• Nền tảng của hóa sinh học
• trao đổi chất protein
• RNA trao đổi chất
• nguyên tắc của hóa sinh
• Axit amin
• công nghệ DNA