TAILIEUCHUNG - Microbial production of antimicrobial agents

In a trial to search for a new antibiotic producer a terrestrial actinomycete was isolated from AL-alameen soil which proved to be a potential candidate for the production of active metabolites against E. coli 25922 and Staphylococcus aureus 25923. | 2019 8 12 1439-1452 EXCELLENT PUBLISHERS International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 8 Number 12 2019 Journal homepage http Original Research Article https Microbial Production of Antimicrobial Agents Bassma H. Elwakil1 Mahmoud M. Abdelaziz2 Kareem M. Mahgoub2 Ahmed M. Abdelrasheed2 Ahmed N. Ameen2 and Zakia A. Olama2 department of Allied Medical Science Pharos University in Alexandria Egypt department of Botany and Microbiology Faculty of Science Alexandria Egypt ABSTRACT Keywords Pentadecanoic acid 14-methyl- methyl ester Hexadecanoic acid Article Info Accepted 12 November 2019 Available Online 10 December 2019 In a trial to search for a new antibiotic producer a terrestrial actinomycete was isolated from AL-alameen soil which proved to be a potential candidate for the production of active metabolites against E. coli 25922 and Staphylococcus aureus 25923. It was identified phenotypicallyas Streptomyces sp. The optimum activity was obtained when the organism was grown on glycerol as a sole carbon source at 30 C and pH for 192 h. The highest metabolic activity noticed intracellulary and it was approved with MIC values. In a trial to test the combined activity of the extract and some antibiotics synergistic action was noticed with ceftriaxone. Further investigations were applied to the extract for its active components using TLC and GC-MS which indicated that Pentadecanoic acid 14-methyl- methyl ester Hexadecanoic acid methyl ester and 2 4-bis 1 1-dimethylethyl - Phenol were the potent active components. Toxicity test will be evaluated for the active components as well as the crude extract. Introduction Antibiotics are one of the most important weapons in fighting bacterial infections and have greatly benefited the health-related quality of human life since their introduction. However over the past few decades these health benefits are .

• Sinh học
• Pentadecanoic acid
• 14 methyl methyl ester
• Hexadecanoic acid
• Microbial production
• Antimicrobial agents
• Nelson’s pediatric antimicrobial therapy
• Choosing among antifungal agents
• Antimicrobial therapy for newborns
• Antimicrobial therapy according
• Clinical syndromes
• Specific parasitic pathogens
• Urease inhibitors
• Phosphorated compounds
• The development of urease inhibitors
• Against pathogenic bacteria
• In vitro activities
• Antimicrobial agents against uropathogenic isolates
• Ahafo regional hospital
• Probable antibiotic alternatives
• Uropathogenic isolates in UTIs
• Alphabetic listing of antimicrobials
• Adverse reactions to antimicrobial agents
• Drug interactions
• Antibiotic therapy
• health
• care
• primary
• report
• Antimicrobial
• Agents
• Varaprasad Bobbarala
• Community acquired pneumonia
• Streptococcus pneumoniae
• Microbiological profile of cases
• Antimicrobial susceptibility testing
• Etiological agents
• BMC Chemistry
• 2 Mercaptobenzimidazole
• Biological profile
• Heterocyclic benzimidazole analogues
• Prospective antimicrobial
• Anti proliferative agents
• Schiff base
• Cell cycle
• Cytotoxic agents
• Naphthol diazenyl scaffold
• 2 hydroxy naphthaldehyde azo dyes
• Infections of eye
• Subtropical climate
• Vitreous humor
• Bacterial isolates
• Aetiological Agents of Endophthalmitis
• Report of the committee on infectious diseases
• Infectious diseases
• Related therapy
• Antimicrobial prophylaxis
• Choosing among antibiotics
• Methicillin resistant staphylococcus aureus
• Drug resistant gram negative bacilli
• Thiazole derivatives
• Antimicrobial activity
• Anticancer activity
• Molecular docking
• Benzoxazole molecules
• Biological activities
• Nitrogen heterocyclic rings
• Click synthesis
• Antiproliferative activity
• Lactobacillus acidophilus
• Heat stability
• pH stability
• Storage stability
• Journal of Chemistry
• E Stilbenes
• Azomethine analogues
• Mizoroki–Heck reaction
• Antioxidant activity
• (Thio)barbituric acid
• Antimicrobial effect
• 4 (1H tetrazol 5 yl) benzenaminium chloride
• Acetic anhydride
• Master's thesis of Applied Science
• Master's thesis
• Henry reaction
• Fluoro b methyl b nitrostyrenes
• Partition coefficients
• Log P values
• Azo compounds
• Carbon paste electrode
• Cyclic voltammetry
• Antibacterial agents
• Antifungal agents
• 2 Aminomethylthiazole
• Cobalt complexes
• Enzyme inhibition
• Antioxidant agents
• Diazenyl chalcones
• Heteroaromatic aldehydes
• Pharmaceutical microbiology
• Fundamental features
• Clinical uses
• Antimicrobial drugs
• Bacterial resistance
• Synthetic antimicrobial agents
• Glycopeptide Resistance
• Aminoglycosides
• Empiricism Ruled
• Antibiotic Discovery