TAILIEUCHUNG - Application of tetracycline hydrochloride loaded-fungal chitosan and Aloe vera extract based composite sponges for wound dressing

Chitosan composite material has been used as an efficient drug carrier for potential drug delivery systems in specific cases of wound dressing management. In the present study, g/L of the antibiotic tetracycline hydrochloride (TCH) was loaded into 1% fungal chitosan (FCS) incorporated with of Aloe vera extract (AVE). Two types of sponges were prepared, with and without AVE, such as FCS-AVE-TCH and FCS-TCH, respectively. They were characterized by UV–Visible spectrophotometer, attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), and scanning electron microscopy (SEM). A constant amount of cumulative TCH release was observed from FCS-AVE-TCH composite sponges at the phosphate buffer saline (pH ), they exhibited good antibacterial activity against both Gram-positive and Gram-negative bacteria. Furthermore, the Vero cells (African green monkey kidney cell line) treated by the composites showed augmented cell viability, which suggests that it could be used as a cost-effective, potential wound dressing material. | Application of tetracycline hydrochloride loaded-fungal chitosan and Aloe vera extract based composite sponges for wound dressing

• Y khoa - Dược
• Fungal chitosan
• Aloe vera extract
• Tetracycline hydrochloride
• Wound dressing
• Extract based composite sponges
• Cu chitosan
• Fungal disease
• Maize caused by fusarium verticillioids
• Fusarium verticillioids
• Cu chitosan nanocomposites on control
• The role of chitosan in protection
• Fungal culture and growth
• Sudden death syndrome caused
• Chitinase activity assay in soybean
• The level of chitinase activity
• Anti fungal
• Essential oil
• Primary irritation index
• Chitosan polymer matrix alleviates skin irritation
• Encapsulation of mentha oil