TAILIEUCHUNG - Ebook Harrison principles of internal medicine self-Accessment and board review (15th edition): Part 2

(BQ) Part 2 book "Harrison principles of internal medicine self-Accessment and board review" presents the following contents: Disorders of the gastrointestinal system, disorders of the immune system, connective tissue, and joints; endocrine and metabolic disorders; neurologic disorders; environmental and occupational hazards. | X. DISORDERS OF THE GASTROINTESTINAL SYSTEM QUESTIONS DIRECTIONS Each question below contains five suggested responses. Choose the one best response to each question. X-1. A 56-year-old woman has had profuse watery diarrhea for 3 months. Laboratory studies of fecal water show the following Sodium 39 mmol L Potassium 96 mmol L Chloride 15 mmol L Bicarbonate 40 mmol L Osmolality 270 mosmol kg H2O serum osmolality 280 mosmol kg H2O The most likely diagnosis is A villous adenoma B lactose intolerance C laxative abuse D pancreatic insufficiency E nontropical sprue X-2. A 56-year-old man presents to his internist with jaundice. The patient is receiving no medication and his only symptomatic complaint is mild fatigue over the past 2 months. Physical examination is remarkable only for the presence of scleral icterus. The patient has no significant past medical history. Analysis of serum chemistry reveals the following SGOT pkat L 35 U L SGPT pkat L 35 U L Total bilirubin mol L 7 mg dL Direct bilirubin pmol L 5 mg dL Alkaline phosphatase 12 kat L 720 U L Which of the following is the next most appropriate diagnostic step A CT of the abdomen B Liver biopsy C Review of peripheral blood smear D Endoscopic retrograde cholangiopancreatography ERCP E No further evaluation necessary the patient has Dubin-Johnson syndrome X-3. A 24-year-old patient known to be infected with HIV-1 presents with a 2-week history of intermittent bloody diarrhea urgency abdominal pain and malaise. Stool culture for enteropathogenic organisms is negative and analysis for ova and parasites is similarly unrevealing. The patient is taking no medication. The diarrheal symptoms do not respond to a course of trimethoprim-sulfameth-oxazole. Colonoscopic examination reveals multiple areas of ulceration and mucosal erosion. Biopsy reveals the presence of cells containing a large densely staining nucleus and abundant intracytoplasmic inclusions. The most appropriate therapy for this patient is

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