TAILIEUCHUNG - Ebook Textbook of biochemistry with clinical correlations (4th edition): Part 2

(BQ) Part 2 book "Textbook of biochemistry with clinical correlations" presents the following contents: Amino acid metabolism, purine and pyrimidine nucleotide metabolism, metabolic interrelationships, structure and conformation, repair, synthesis and recombination. | Page 445 Chapter 11 Amino Acid Metabolism Marguerite W. Coomes Overview 446 Incorporation of Nitrogen into Amino Acids 447 Most Amino Acids Are Obtained from the Diet 447 Amino Groups Are Transferred from One Amino Acid to Form 448 Another Pyridoxal Phosphate Is Cofactor for Aminotransferases 449 Glutamate Dehydrogenase Incorporates and Produces Ammonia 450 Free Ammonia Is Incorporated into and Produced from Glutamine 450 Amide Group of Asparagine Is Derived from Glutamine 452 Amino Acid Oxidases Remove Amino Groups 452 Transport of Nitrogen to Liver and Kidney 452 Protein Is Degraded on a Regular Basis 452 Amino Acids Are Transported from Muscle after Proteolysis 453 Ammonia Is Released in Liver and Kidney 453 Urea Cycle 453 Nitrogens of Urea Come from Ammonia and Aspartate 453 Synthesis of Urea Requires Five Enzymes 454 Urea Synthesis Is Regulated by an Allosteric Effector and Enzyme 455 Induction Metabolic Disorders of Urea Synthesis Have Serious Results 455 Synthesis and Degradation of Individual Amino Acids 456 Glutamate Is a Precursor of Glutathione and -Aminobutyrate 457 Arginine Is Also Synthesized in Intestines 457 Ornithine and Proline 458 Serine and Glycine 459 Tetrahydrofolate Is a Cofactor in Many Reactions of Amino Acids 460 Threonine 463 Phenylalanine and Tyrosine 463 Tyrosine Is the First Intermediate in Phenylalanine Metabolism 465 Dopamine Epinephrine and Norepinephrine Are Derivatives of 466 Tyrosine Tyrosine Is Involved in Synthesis of Melanin Thyroid Hormone and 468 Quinoproteins Methionine and Cysteine 469 Methionine Is First Reacted with Adenosine Triphosphate 469 S-Adenosylmethionine Is a Methyl Group Donor 471 AdoMet Is the Precursor of Spermidine and Spermine 472 Metabolism of Cysteine Produces Sulfur-Containing Compounds 473 Tryptophan 474 Tryptophan Is a Precursor of NAD 475 Pyridoxal Phosphate Has a Prominent Role in Tryptophan 476 Metabolism Kynurenine Gives Rise to Neurotransmitters 476 Serotonin and Melatonin

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