TAILIEUCHUNG - COLOR ATLAS OF DERMATOPATHOLOGY_2

Why one more book on dermatopathology? Certainly there are many outstanding encyclopedic textbooks already written and even recently updated. Why one more atlas? Hopefully you will agree that this book is different. We have tried to pair clinical and histologic photographs to enhance the reader’s appreciation for clinical-pathological correlation. In addition, this text is meant to be user friendly whether you are approaching dermatopathology from a background of dermatology or pathology. Herein we hope to share with you our enthusiasm as well as the helpfulness of clinical- pathological as well as pathological-clinical correlation. Ideally after reading through some of our examples, the next time you look through the. | 17 Glandular Adnexal Apocrine and Eccrine Neoplasms Timothy H. McCalmont Department of Clinical Pathology and Dermatology and UCSF Dermatopathology Service University of California San Francisco California . CONTENTS MICROANATOMICAL AND EMBRYOLOGICAL CONSIDERATIONS CLASSIFICATION OF GLANDULAR ADNEXAL NEOPLASMS EXAMPLES OFADNEXAL NEOPLASMS Apocrine Neoplasms B Syringoma B Poroma B Hidradenoma B ApocrineAdenoma B Spiradenoma B Cylindroma B Adnexal Carcinoma Eccrine Neoplasms B Tubulopapillary Papillary Adenoma andAdenocarcinoma The nosology of adnexal neoplasms has been confused and confusing for decades and much of the mystification of the past was wrought by the lack of logical classification. Classification proposals and inferences regarding lineage from the authorities of the past were often contradictory and to a lesser extent this problem persists at the present time. This is in part a consequence of the fact that broad conclusions regarding lineage and classification were based on enzyme histochemical attributes that lacked established specificity and were never properly assessed in the context of controlled trials. Enzyme histochemistry enjoyed a brief flash of activity in the late 1960s but has proved to be of dubious value over time. Although the number of cases studied by enzymatic analysis was very small and the assessment was based mostly upon uncontrolled qualitative judgments the results became the basis for conclusions regarding lineage that persisted for decades. The method has not stood the test of time although it lingers on in the minds of some and in some textbook chapters. Indeed enzyme histochemistry is no longer generally available as a method of analysis. In short enzyme histochemistry contributed to the evolution of misguided classification schemes that have persisted in dermatology and dermatopathology. Only recently has the lack of credibility of enzyme analysis led to a rethinking of this field. Surprisingly relatively compelling .

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