TAILIEUCHUNG - Báo cáo sinh học: "Persistence of accuracy of genome-wide breeding values over generations when including a polygenic effect"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Persistence of accuracy of genome-wide breeding values over generations when including a polygenic effect | Genetics Selection Evolution BioMed Central Research Persistence of accuracy of genome-wide breeding values over generations when including a polygenic effect Trygve R Solberg 1 Anna K Sonesson2 John A Woolliams1 3 Jorgen 0degard2 1 and Theo HE Meuwissen1 Address Norwegian University of Life Sciences Department of Animal and Aquacultural Sciences PO Box 5003 N-1432 As Norway 2NOFIMA Marine PO Box 5010 N-1432 As Norway and 3Roslin Institute Edinburgh Roslin Midlothian EH25 9PS UK Email Trygve R Solberg - Anna K Sonesson - John A Woolliams - Jorgen 0degard - Theo HE Meuwissen - Corresponding author Open Access Published 29 December 2009 Received 30 January 2009 z- z I nvmnKvnz ZI rAccepted 29 December 2009 Genetics Selection Evolution 2009 41 53 doi 1297-9686-41-53 This article is available from http content 41 1 53 2009 Solberg et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background When estimating marker effects in genomic selection estimates of marker effects may simply act as a proxy for pedigree . their effect may partially be attributed to their association with superior parents and not be linked to any causative QTL. Hence these markers mainly explain polygenic effects rather than QTL effects. However if a polygenic effect is included in a Bayesian model it is expected that the estimated effect of these markers will be more persistent over generations without having to re-estimate the marker effects every generation and will result in increased accuracy and reduced .

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