TAILIEUCHUNG - Báo cáo sinh học: "Large-scale association study for structural soundness and leg locomotion traits in the pig"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Large-scale association study for structural soundness and leg locomotion traits in the pig | Genetics Selection Evolution BioMed Central Research Large-scale association study for structural soundness and leg locomotion traits in the pig Bin Fan1 2 Suneel K Onteru1 Benny E Mote1 Timo Serenius1 Kenneth J Stalder1 and Max F Rothschild 1 Open Access Address Department of Animal Science and Center for Integrated Animal Genomics Iowa State University Ames IA 50011 USA and 2Key Laboratory of Agricultural Animal Genetics Breeding and Reproduction Ministry of Education College of Animal Science and Technology Huazhong Agricultural University Wuhan 430070 PR China Email Bin Fan - bfan@ Suneel K Onteru - sonteru@ Benny E Mote - bmote@ Timo Serenius - Kenneth J Stalder - stalder@ Max F Rothschild - mfrothsc@ Corresponding author Published 21 January 2009 Received 22 December 2008 Genetics Selection Evolution 2009 41 14 doi l297-9686-4l-l4 Accepted 21 January 2009 This article is available from http content 4l l l4 2009 Fan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Identification and culling of replacement gilts with poor skeletal conformation and feet and leg FL unsoundness is an approach used to reduce sow culling and mortality rates in breeding stock. Few candidate genes related to soundness traits have been identified in the pig. Methods In this study 2066 commercial females were scored for l7 traits describing body conformation and FL structure and were used for association analyses. Genotyping of l2l SNPs derived from 95 genes was implemented using Sequenom s MassARRAY system. Results Based on the association results from single trait and principal components using mixed linear .

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